2012 Fiscal Year Final Research Report
Development of basic technology to simplify biocatalytic processes for the production of chemicals
| Project/Area Number |
22360343
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biofunction/Bioprocess
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| Research Institution | Osaka University |
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Principal Investigator |
OHTAKE Hisao 大阪大学, 工学研究科, 教授 (10127483)
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| Co-Investigator(Kenkyū-buntansha) |
HONDA Khosuke 大阪大学, 工学研究科, 准教授 (90403162)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 耐熱性酵素 / 生体触媒 / バイオプロセス / 加熱処理 |
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| Research Abstract |
We have developed a simple, new bioproduction platform which is potentially applicable to the synthesis of specialty chemicals.The newly developed process has many potential advantages: (i) whatever target metabolites can be specifically produced; (ii) enzyme purification is not required; (iii) no by-product is formed; (iv) bioconversions can be performed using a simple reactor without elaborate process control; and (v) reaction can be prevented from microbial contamination
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[Journal Article] Synthetic metabolic engineering-A novel, simple technology for designing a chimeric metabolic pathway-2012
Author(s)
Ye, X., Honda, K., Sakai, T., Okano, K., Omasa, T., Hirota , R., Kuroda, A., and Ohtake, H.
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Journal Title
Microb. Cell Fact.
Volume: 11
Pages: 212
Peer Reviewed
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[Journal Article] Analyses of both the alkB gene transcriptional start site and alkB promoter inducing properties in Rhodococcus sp2011
Author(s)
Cappelletti, M., Fedi, S., Frascari, D., Ohtake, H., Turner, R.J., and Zannoni, D
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Journal Title
BCP1 as grown on n-alkanes. Appl. Environ. Microbiol.
Volume: 77
Pages: 1619-1627
Peer Reviewed
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