2012 Fiscal Year Final Research Report
Identification of transporters involved in excretion of toxic sulfate and borate by seawater fish
| Project/Area Number |
22370029
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Animal physiology/Animal behavior
|
|---|
| Research Institution | Tokyo Institute of Technology |
|---|
Principal Investigator |
HIROSE Shigehisa 東京工業大学, 大学院・生命理工学研究科, 教授 (10134199)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
KATO Akira 東京工業大学, 大学院・生命理工学研究科, 助教 (40311336)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Keywords | 動物生理化学 |
|---|
| Research Abstract |
Sulfate and borate are abundant anion in seawater (SW), and excretion of excess sulfate and borate from ingested SW is essential for marine fish to survive because they are toxic. Marine teleosts excrete sulfate and borate via the urine produced in the kidney. The transporters that secrete and concentrate sulfate and borate in the urine have not previously been identified. Here, we have identified and characterized candidates for the long-sought transporters by using euryhaline pufferfish mefugu.
|
