2012 Fiscal Year Final Research Report
Basic Analysis of Oxidative Fermentation of Acetic Acid Bacteriaand Development of Novel Fermentation System
| Project/Area Number |
22380054
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | Yamaguchi University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
YAKUSHI Toshiharu 山口大学, 医学系研究科, 准教授 (30324388)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 酸化発酵 / 酢酸菌 / キノプロテイン / フラボプロテイン / 末端オキシダーゼ |
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| Research Abstract |
We did molecular level study of membrane-bound quinoproteins or flavoproteins and respiratory chain of “oxidative fermentation”, especially for sorbose, dihydroxyacetone and acetic acid fermentations, of acetic acid bacteria. As the results
we elucidated 1) electron transfer route of the respiratory chain
2) finding of novel oxidation reaction of the enzymes
3) findings of enzymes for intracellular assimilation
and also we found novel enzymes based on the biochemical or bioinformatic analyses.
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[Journal Article] The crystal structure of L-sorbose reductase from Gluconobacter frateuriicomplexed with NADPH and L-sorbose2011
Author(s)
Kubota K, Nagata K, Okai M, Miyazono KI, Soemphol W, Ohtsuka J, Yamamura A, Saichana N, Toyama H, Matsushita K, Tanokura M
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Journal Title
J Mol Biol
Volume: 407(4)
Pages: 543-555
DOI
Peer Reviewed
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