2012 Fiscal Year Final Research Report
Acquisition of the meiotic and mitotic competence during oocyte growth
| Project/Area Number |
22380156
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Basic veterinary science/Basic zootechnical science
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| Research Institution | The University of Tokyo |
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Principal Investigator |
AOKI Fugaku 東京大学, 大学院・新領域創成科学研究科, 教授 (20175160)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 発生 / 成熟能 / 発生能 |
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| Research Abstract |
Mammalian oocytes acquire the competence for meiotic maturation ad subsequent development during their growth in the ovaries. However, a part of fully grown oocytes do not have this competence. In the present study, to determine the factor(s) involved in this competence, I conducted the transcriptome analysis for the oocytes with and without the competence. Several candidates for the factor were obtained from this analysis. By inhibiting the expression of these candidates in the growing oocytes, I determined the target factors.
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Research Products
(14 results)
