2013 Fiscal Year Final Research Report
Vertical transmission pattern of pathogens cause abortion of domestic animals
| Project/Area Number |
22380158
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Basic veterinary science/Basic zootechnical science
|
|---|
| Research Institution | Gifu University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
OHYA Kenji 岐阜大学, 応用生物科学部, 准教授 (50402219)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
TAKASU Masaki 岐阜大学, 応用生物科学部, 准教授 (00503327)
|
|---|
| Project Period (FY) |
2010-04-01 – 2014-03-31
|
| Keywords | 胎盤 / 家畜 / トキソプラズマ |
|---|
| Research Abstract |
In this study, the dissemination of intracellular pathogen from maternal blood flow to the placenta was revealed. Even in the case of pathogens, which preferencially infect to the placenta, drastical accumulation of the infected maternal leukocytes was not observed in the placenta. It may be because the lack of expression of molecules related with cell adhesion on the most surface layer of the placenta. Physical disruption of the layer must be important for vertical transmission of intracellular pathogens.
|
