2012 Fiscal Year Final Research Report
Regulation of virulence expression by retron including reverse transcriptase gene and roles as mobile genetic elements
| Project/Area Number |
22390083
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Bacteriology (including Mycology)
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| Research Institution | Hiroshima University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SHIMAMOTO Toshi 広島大学, 大学院・生物圏科学研究科, 助教 (70583136)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 病原性 / 遺伝子発現制御 / 逆転写酵素,ゲノム / Vibrio cholerae / レトロン / msDNA |
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| Research Abstract |
The orf540gene present downstream of the reverse transcriptase gene (ret) in retron-Vc95 was found to be related to pathogenicity in Vibrio choleraeO139. New retrons were isolated and identified from a clinical isolate of V. choleraenon-O1, non-O139 and an environmental isolate of V. mimicus. Plasmid-derived retron of a clinical isolate of Escherichia coliand new retron of Yersinia frederikseniiwere also analysed.
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