Assessment of risk factors for ovarian cancer including serum equol concentration by histopathology with a case-control study

2012 Fiscal Year Final Research Report

• Project/Area Number: 22390135
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Public health/Health science
• Research Institution: Sapporo Medical University
• Principal Investigator: MORI Mitsuru 札幌医科大学, 医学部, 教授 (50175634)
• Co-Investigator(Kenkyū-buntansha): SAITO Tsuyoshi 札幌医科大学, 医学部, 教授 (90145566)
• Project Period (FY): 2010 – 2012
• Keywords: 卵巣がん / 症例対象研究 / イソフラボン / エコール / ダイゼイン / 業理組織型

Research Abstract

We conducted a case-control study on association of serum components with ovarian cancer (OC) risk. OC cases (N=71) and their controls (N=80) were recruited from inpatients at Sapporo Medical University Hospital. Unconditional logistic regression analysis was used for adjustment of age, number of love-births, and BMI. As a result from the multivariate analysis, serum daizein level was significantly associated with decreased risk of OC (P

Research Products

• [Journal Article] 婦人科がん-概論-,がんの予防 (2012)
  • Author(s): 森 満, 朝倉純代
  • Journal Title: 日本臨床 Volume: 70 Pages: 10-14
  • Peer Reviewed
• [Presentation] 卵巣がんにおける表層上皮由来とされる各腺がんの血中 Isoflavone 類、 Insulin およびAdiponectin 濃度を含む症例対照研究 (2012)
  • Author(s): 男澤聖子, 田中綾一, 赤坂 憲, 大西浩文, 朝倉純代, 伊東英樹, 斉藤重幸, 三浦哲嗣, 斉藤 豪, 森 満
  • Organizer: 第35回日本がん疫学・分子疫学研究会総会
  • Place of Presentation: 広島
  • Year and Date: 20120705-06
• [Presentation] A case-control studyto assess association of serum isoflavones, adiponectin, and insulin with ovarian cancer risk (2012)
  • Author(s): Mori M, Otokozawa S, Asakura S, Ohnishi H, Akasaka S, Saitoh S, Miura T, Tanaka R, Itoh H, Saitoh T
  • Organizer: 71st Annual Meeting of Japanese Cancer Association
  • Place of Presentation: Sapporo
  • Year and Date: 2012-09-19
• [Presentation] 血中 Isoflavone 類, Insulin 濃度を含む卵巣がんのCase-Control study (2011)
  • Author(s): 男澤聖子, 伊東英樹, 斎藤 豪 , 赤坂憲, 斉藤重幸, 三浦哲嗣, 朝倉純代, 大西浩文, 森 満.
  • Organizer: 第18回日本がん予防学会, 第34回日本がん疫学分子疫学研究会, がん予防大会 2011
  • Place of Presentation: 京都
  • Year and Date: 20110619-20