2012 Fiscal Year Final Research Report
Development and establishment of the novel method for the objective diagnosis of Meniere's disease using advanced MRI techniques
| Project/Area Number |
22390233
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Nagoya University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NAKASHIMA Tsutomu 名古屋大学, 大学院・医学系研究科, 教授 (30180277)
NIHASHI Takashi 名古屋大学, 医学部附属病院, 講師 (00426496)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 磁気共鳴医学 / 耳科学 / 高磁場 / 造影剤 / メニエール病 |
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| Research Abstract |
To develop less invasive and robust objective diagnostic method for Meniere’s disease, we developed various methods as follows; custom built dedicated four channel coil which has 2 times SNR compared to commercial coil. Optimal timing of imaging after iv-Gd was 3.5h-4.5h. We developed positive endolymph image (PEI). For the image processing, we developed a method to separately visualize bone, endolymph and perilymph on a single image. We subtractPEI from PPI, resulting in the HYDROPS image. We also developed HYDROPS2 image etc by the subtraction of T2 from PPI. Additionally, we succeeded the semi-quantification of endolymph size by iv-Gd.
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Research Products
(40 results)
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[Journal Article] A perspective from magnetic resonance imaging findings of the inner ear: Relationships among cerebrospinal, ocular and inner ear fluids2012
Author(s)
Nakashima T, Sone M, Teranishi M, Yoshida T, Terasaki H, Kondo M, Yasuma T, Wakabayashi T, Nagatani T, Naganawa S
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Journal Title
Auris NasusLarynx
Volume: 39(4)
Pages: 345-55
Peer Reviewed
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