2012 Fiscal Year Final Research Report
Investigation the mechanism and the role of RNA activation by micro RNA in pancreatic cancer
| Project/Area Number |
22390258
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Digestive surgery
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| Research Institution | Kyushu University |
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Principal Investigator |
NAGAI Eishi 九州大学, 医学研究院, 准教授 (30264021)
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| Co-Investigator(Kenkyū-buntansha) |
TOMA Hiroki 九州大学, 医学研究院, 共同研究員 (80437780)
EGAMI Takuya 九州大学, 医学研究院, 共同研究員 (40507787)
MIZUMOTO Kazuhiro 九州大学, 大学病院, 准教授 (90253418)
UEDA Junji 九州大学, 大学病院, 助教 (90529801)
TOMINAGA Yohei 九州大学, 医学研究院, 共同研究員 (90304823)
OHUCHIDA Kenoki 九州大学, 先端イノベーションセンター, 講師 (20452708)
TANAKA Masao 九州大学, 医学研究院, 教授 (30163570)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 膵癌 / microRNA |
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| Research Abstract |
We investigated miRNA expression in pancreatic cancer. We found miR-10b expression is overexpressed and miR-X(now submitting) expression is inhibited in pancreatic cancer. We also found miR-10b is related with pancreatic cancer invasiveness and its expression is related with poor prognosis.
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[Journal Article] Invasive carcinoma derived from intestinal-type intraductal papillary mucinous neoplasm is associated with minimal invasion, colloid carcinoma, and less invasive behavior , leading to a better prognosis2011
Author(s)
Nakata K, Ohuchida K, Aishima S, Sadakari Y, Kayashima T, Miyasaka Y, Nagai E, Mizumoto K, Tanaka M
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Journal Title
Pancreas
Volume: 40(4)
Pages: 581-7
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