Sulcal neuroanatomy of human brain

2012 Fiscal Year Final Research Report

• Project/Area Number: 22390275
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Cerebral neurosurgery
• Research Institution: Osaka University
• Principal Investigator: YOSHIMINE Toshiki 大阪大学, 医学系研究科, 教授 (00201046)
• Co-Investigator(Kenkyū-buntansha): HIRATA Masayuki 大阪大学, 医学系研究科, 特任准教授 (30372626) ; J Morris Shayne 大阪大学, 医学部付属病院, 医員 (70542116) ; YANAGISAWA Takufumi 大阪大学, 医学系研究科, 助教 (90533802) ; KISHIMA Haruhiko 大阪大学, 医学系研究科, 講師 (10332743) ; SAITOH Youichi 大阪大学, 教授 (20252661) ; HASHIMOTO Naoya 大阪大学, 医学系研究科, 准教授 (90315945) ; GOTOU Tethu 大阪大学, 医学系研究科, 助教
• Co-Investigator(Renkei-kenkyūsha): MATSUSHITA Kojiro 大阪大学, 医学系研究科, 特任助教 (30531793)
• Project Period (FY): 2010 – 2012
• Keywords: 脳溝 / 神経接続性 / 皮質脳波 / コヒーレンス / ファイバートラッキング

Research Abstract

We performed 3 dimensional neuroanatomical analyses of the central sulcus. The shape of the central sulcus was delineated from MR images using automatic sulcus detection software. Protrusion and surface area of the hand knob was significantly larger in the left side of the anterior wall of the central sulcus. The most medial portion of the hand area was stable in the axial MR images, which was meant to be useful as the origin of the local coordinate system. We applied this technique to intracranial electrode sheet manufacturing. We established a manufacturing method of automatic brain surface detection, mold design using 3D CAD, rapid manufacturing of the mold using a 3D printer, and manufacturing silicone electrode sheet fitting to individual brain surfaces. A high density 3D electrode array made using this method was used for an ALS patient in our clinical research of brain machine interfaces.

Research Products

• [Journal Article] Clinical application of neuromagnetic recordings: from functional imaging to neural decoding (2013)
  • Author(s): Hirata M, Yoshimine T
  • Journal Title: IEICE Trans Electron Volume: 96-C(3) Pages: 313-319
• [Journal Article] Regulation of motor representation by phase-amplitude coupling in the sensorimotor cortex (2012)
  • Author(s): Yanagisawa T, Yamashita O, Hirata M, Kishima H, Saitoh Y, Goto T, Yoshimine T, Kamitani Y
  • Journal Title: J Neurosci Volume: 32(44) Pages: 15467-15475
• [Journal Article] Neural decoding of unilateral upper limb movements using single trial MEG signals (2012)
  • Author(s): Sugata H, Goto T, Hirata M, Yanagisawa T, Shayne M, Matsushita K, Yoshimine T, Yorifuji S
  • Journal Title: Brain Res Volume: 1468 Pages: 29-37
• [Journal Article] Altered extrafocal iomazenil activity in mesial temporal lobe epilepsy (2012)
  • Author(s): Hosomi K, Kishima H, Oshino S, Hirata M, Tani N, Maruo T, Hui Ming Khoo, Shimosegawa E, Hatazawa J, Kato A, Yoshimine T
  • Journal Title: Epilepsy Res Volume: 103(2-3) Pages: 195-204
• [Journal Article] Differential responses of primary auditory cortex in autistic spectrum disorder with auditory hypersensitivity (2012)
  • Author(s): Matsuzaki J, Kagitani-Shimono K, Goto T, Sanefuji W, Yamamoto T, Sakai S, Uchida H, Hirata M, Mohri I, Yorifuji S, Taniike M
  • Journal Title: Neuroreport Volume: 23 Pages: 113-118
• [Journal Article] Movement-related neuromagnetic fields and decoding performances of single trial classifications in unilateral upper limb movements (2012)
  • Author(s): Sugata H, Goto T, Hirata M, Yanagisawa T, Shayne M, Matsushita K, Yoshimine T, Yorifuji S
  • Journal Title: Neuroreport Volume: 23(1) Pages: 16-20
• [Journal Article] Electrocorticographic control of a prosthetic arm in paralyzed patients (2011)
  • Author(s): Yanagisawa T, Hirata M, Saitoh Y, Kishima H, Matsushita K, Goto T, Fukuma R, Yokoi H, Kamitani Y, Yoshimine T
  • Journal Title: Annal Neurol Volume: 71(3) Pages: 353-361
• [Journal Article] A high-linearity low-noise amplifier with variable bandwidth for neural recording systems (2011)
  • Author(s): Yoshida T, Sueishi K, Iwata A, Matsushita K, Hirata M, Suzuki T
  • Journal Title: Jap J Applied Physics Volume: 50
• [Journal Article] Motor restoration based on the brain machine interface using brain surface electrodes: real time robot control and a fully-implantable wireless system (2011)
  • Author(s): Hirata M, Matsushita K, Yanagisawa T, Goto T, Morris S, Yokoi H, Suzuki T, Yoshida T, Sato F, Kawato M, Yoshimine T
  • Journal Title: Advanced robotics Volume: 26 Pages: 399-408
• [Journal Article] A fully-implantable wireless system for human brain-machine interfaces using brain surface electrodes: W-HERBS (2011)
  • Author(s): Hirata M, Matsushita K, Suzuki T, Yoshida T, Sato F, Morris S, Yanagisawa T, Goto T, Kawato M, Yoshimine T
  • Journal Title: IEICE Trans Commun Volume: E94-B(9) Pages: 2448-2453
• [Journal Article] Deep brain stimulation of the subthalamic nucleus improves temperature sensation in patients with Parkinson's disease (2011)
  • Author(s): Maruo T, Saitoh Y, Hosomi K, Kishima H, Shimokawa T, Hirata M, Goto T, Morris S, Harada Y, Yanagisawa T, Aly MM, Yoshimine T
  • Journal Title: Pain Volume: 152(4) Pages: 860-5
• [Journal Article] Real-time control of a prosthetic hand using human electrocorticograms (2011)
  • Author(s): Yanagisawa T, Hirata M, Saitoh Y, Goto T, Kishima H, Fukuma R, Yokoi H, Kamitani Y, Yoshimine T
  • Journal Title: J Neurosurg Volume: 114(6) Pages: 1715-22
• [Journal Article] Frequency-dependent spatiotemporal distribution of cerebral oscillatory changes during silent reading: a magnetoencephalograhic group analysis (2011)
  • Author(s): Goto T, Hirata M, Umekawa Y, Yanagisawa T, Shayne M, Saitoh Y, Kishima H, Yorifuji S, Yoshimine T
  • Journal Title: Neuroimage Volume: 54(1) Pages: 560-567
• [Journal Article] Quantitative analysis of phosphenes induced by navigation-guided repetitive transcranial magnetic stimulation (2011)
  • Author(s): Tani N, Hirata M, Motoki Y, Saitoh Y, Yanagisawa T, Goto T, Hosomi K, Kozu A, Yorifuji S, Yoshimine T
  • Journal Title: Brain stimulation Volume: 4(1) Pages: 28-37
• [Journal Article] Magnetoencephalogram (2010)
  • Author(s): Barnes G, Hillebrand A, Hirata M
  • Journal Title: Scholarpedia Volume: 5(7) Pages: 3172
  • URL: http://www.scholarpedia.org/article/Magnetoencephalogram
• [Journal Article] Modulation of neuronal activity after spinal cord stimulation for neuropathic pain; H(2)(15)O PET study (2010)
  • Author(s): Kishima H, Saitoh Y, Oshino S, Hosomi K, Ali M, Maruo T, Hirata M, Goto T, Yanagisawa T, Sumitani M, Osaki Y, Hatazawa J, Yoshimine T
  • Journal Title: Neuroimage Volume: 49(3) Pages: 2564-2569
• [Journal Article] Neuroimaging study on brain asymmetries in situs inversus totalis (2010)
  • Author(s): Ihara A, Hirata M, Fujimaki N, Goto T, Umekawa Y, Fujita N, Terazono Y, Matani A, Wei Q, Yoshimine T, Yorifuji S, Murata T
  • Journal Title: J Neurol Sci Volume: 288(1-2) Pages: 72-78
• [Journal Article] Language dominance and mapping based on neuromagnetic oscillatory changes: comparison with invasive procedures (2010)
  • Author(s): Hirata M, Goto T, Barnes G, Umekawa Y, Yanagisawa T, Kato A, Oshino T, Kishima H, Hashimoto N, Saitoh Y, Tani N, Yorofuji S, Yoshimine T
  • Journal Title: J Neurosurg Volume: 112(3) Pages: 528-538
• [Presentation] Current status and problems of neurosurgery in Asia (2013)
  • Author(s): Yoshimine T
  • Organizer: Japan-Asia Neurosurgical Forum
  • Place of Presentation: Fukuoka(Japan)
  • Year and Date: 2013-03-09
• [Presentation] Clinical BMI Roadmap in Japan (2013)
  • Author(s): Yoshimine T
  • Organizer: 2013 International Workshop on Clinical Brain Neural Machine Interface Systems
  • Place of Presentation: Houston, Texas
  • Year and Date: 2013-02-25
• [Presentation] Clinical application of neuromagnetic recordings: from functional mapping to brain-machine interfaces (2013)
  • Author(s): Hirata M
  • Organizer: 2013 Neurology & Neurosurgery Forum
  • Place of Presentation: Taipei (Taiwan)
  • Year and Date: 2013-01-13
• [Presentation] Connectivity changes in the epileptic brain (2012)
  • Author(s): Yoshimine T
  • Organizer: 6th Asian Epilepsy Surgery Congress
  • Place of Presentation: Busan(Korea)
  • Year and Date: 2012-11-09
• [Presentation] Towards clinical application of brain-machine interfaces based on electrocorticograms (2012)
  • Author(s): Hirata M, Yanagisawa T, Matsushita K, Sugata H, Morris S, Kageyama Y, Kishima H, Saitoh Y, Kamitani Y, Suzuki T, Yokoi H, Nishimura Y, Yoshida T, Sato F, Kawato M, Yoshimine T
  • Organizer: The International Symposium on Clinical Application of Brain-Machine Interface (BMI)
  • Place of Presentation: Osaka (Japan)
  • Year and Date: 2012-10-20
• [Presentation] Contour Fitting High Density Personalized 3 Dimensional Cortical Electrodes (2012)
  • Author(s): Hirata M, Shayne M
  • Organizer: Materialize World Conference 2012
  • Place of Presentation: Leuven (Belgium)
  • Year and Date: 2012-04-18
• [Presentation] Neural Decoding of Cortical Motor Function in Chronically Paralyzed Patients (2012)
  • Author(s): Yoshimine T
  • Organizer: Neural Decoding of Cortical Motor Function in Chronically Paralyzed Patients
  • Place of Presentation: Taipei(Taiwan)
  • Year and Date: 2012-04-13
• [Presentation] A Fully-Implantable Wireless System for Human Brain-Machine Interfaces using Brain Surface Electrodes:W-HERBS (2012)
  • Author(s): Hirata M
  • Organizer: Bielefeld University-Osaka University Workshop 2012
  • Place of Presentation: Osaka
  • Year and Date: 2012-03-21
• [Presentation] Human Brain-Machine Interfaces using Brain Surface Electrodes (2012)
  • Author(s): Hirata M
  • Organizer: Workshop on Cognitive Neuroscience Robotics
  • Place of Presentation: Genova (Italy)
  • Year and Date: 2012-03-13
• [Presentation] A Fully- implantable Wireless System for Human Brain-Machine Interfaces using Brain Surface Electrodes: W-HERBS (2011)
  • Author(s): Hirata M, Matsushita K, Suzuki T, Yoshida T, Sato F, Morris S, Yanagisawa T, Goto T, Kawato M, Yoshimine T
  • Organizer: The 41st annual meeting of Society for Neuroscience
  • Place of Presentation: Washington
  • Year and Date: 2011-11-13
• [Presentation] Connecting Robot to Brain (2011)
  • Author(s): Hirata M
  • Organizer: The 4th Symposium on Cognitive Neuroscience Robotics
  • Place of Presentation: 大阪
  • Year and Date: 2011-05-13
• [Presentation] Human brain-machine interface (BMI) (2011)
  • Author(s): Hirata M
  • Organizer: Osaka-UW Workshop 2011
  • Place of Presentation: Seatle
  • Year and Date: 2011-03-17
• [Presentation] An integrative BMI approach for functional restoration using human electrocorticograms (2010)
  • Author(s): Hirata M, Yanagisawa T, Goto T, Matsushita K, Suzuki T, Yokoi H, O Sakura, Yoshida T, Sato F, Fujii N, Ushiba J, Saitoh Y, Sawada J, Kishima H, Kamitani Y, Yoshimine T
  • Organizer: The 40th annual meeting of Society for Neuroscience
  • Place of Presentation: San Diego
  • Year and Date: 2010-11-17
• [Presentation] Neurophysiological approach to language function based on event-related oscillatory changes: from functional mapping to brain-machine interface (2010)
  • Author(s): Hirata M, Goto T, Yanagisawa T, Inui M, Kishima H, Saitoh Y, Hosomi K, Maruo T, Shayne M, Yorifuji S, Yoshimine T
  • Organizer: 29th International Congress of Clinical Neurophysiology
  • Place of Presentation: Kobe
  • Year and Date: 2010-10-30
• [Presentation] Connecting Robot and Brain (2010)
  • Author(s): Hirata M
  • Organizer: Bielefeld-Osaka Workshop 2010
  • Place of Presentation: Bielefeld, Germany
  • Year and Date: 2010-10-12
• [Presentation] Brain-machine interface using human brain surface electrodes (2010)
  • Author(s): Hirata M
  • Organizer: Bielefeld-Osaka Workshop 2010
  • Place of Presentation: Bielefeld, Germany
  • Year and Date: 2010-10-11
• [Book] Technological Advancements in Biomedicine for Healthcare Applicatiions (2012)
  • Author(s): Hirata M, Yanagisawa T, Matsushita K, Sugata H, Kamitani Y, Suzuki T, Yokoi H, Goto T, Morris S, Saitoh Y, Kishima H, Kawato M, Yoshimine T
  • Total Pages: 362-374
  • Publisher: IGI Global Proof
• [Remarks] 大阪大学大学院 医学系研究科 脳神経外科学講座ホームページ
  • URL: http://www.nsurg.med.osaka-u.ac.jp/school/index.html
• [Patent(Industrial Property Rights)] Machine Control Device, Machine System, Machine Control Method, and Recording Medium Storing Machine Control Program (2013)
  • Inventor(s): Hirata M, Yanagisawa T, Kamitani Y, Yokoi H, Yoshimine T, Goto T, Fukuma R, Kato R
  • Industrial Property Rights Holder: Osaka University, ATR, The University of Tokyo
  • Industrial Property Number: US8396546
  • Acquisition Date: 2013-03-12
  • Overseas
• [Patent(Industrial Property Rights)] 体内埋込装置のケーシングと体内埋込装置、および体内埋込装置のケーシングの製造方法、および体内埋込装置を用いた治療支援方法 (2012)
  • Inventor(s): 平田雅之、吉峰俊樹、松下光次郎、後藤哲、柳澤琢史、鈴木隆文、吉村眞一
  • Industrial Property Rights Holder: 国立大学法人大阪大学、国立大学法人東京大学、株式会社飛鳥電機株式会社
  • Industrial Property Number: 米国出願番号 13/510,841
  • Filing Date: 2012-05-18
  • Overseas
• [Patent(Industrial Property Rights)] 頭蓋内電極構造体およびその製造方法 (2012)
  • Inventor(s): 平田雅之、吉峰俊樹、齋藤洋一、柳澤琢史、後藤 哲
  • Industrial Property Rights Holder: 国立大学法人大阪大学
  • Industrial Property Number: 特許5126710
  • Acquisition Date: 2012-11-09