Development of treatment for injury of central and peripheral nervous system

2012 Fiscal Year Final Research Report

• Project/Area Number: 22390333
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Plastic surgery
• Research Institution: Tazuke Kofukai Medical Research Institute
• Principal Investigator: SUZUKI Yoshihisa 公益財団法人田附興風会, 医学研究所 第5研究部, 研究主幹 (30243025)
• Co-Investigator(Renkei-kenkyūsha): NAKATANI Toshio 関西医科大学, 医学部, 教授 (70188978) ; TANIHARA Masao 奈良先端科学技術大学院大学, 物質創成科学研究科, 教授 (50294286)
• Project Period (FY): 2010 – 2012
• Keywords: 細胞培養 / 移植学

Research Abstract

Intrathecal transplantation of autologous bone marrow-derived mononuclear cells for treatment of the patients with spinal cord injury was conducted to assess the safety and feasibility. Ten patients were included. No adverse associated with the treatment responses were observed.

Research Products

• [Journal Article] Autotransplanting of Bone Marrow-Derived Mononuclear Cells for Complete Cases of Canine Paraplegia and Loss of Pain Perception, Secondary to Intervertebral Disc Herniation (2012)
  • Author(s): Tamura ,K,. Harada, Y,. Nagashima ,N,. Kunimi, M,. Itoi, T,. Ishino, H., Yogo, T., Nezu, Y., Hara, Y., Suzuki, Y., Ide, C., Tagawa, M
  • Journal Title: Experimental and Clinical Transplantation Volume: 3 Pages: 263-272
• [Journal Article] Administration of cultured autologous bone marrow stromal cells into cerebrospinal fluid in spinal injury patient: a pilot study (2012)
  • Author(s): Saito, F., Nakatani, T., Iwase, M., Maeda, Y., Murao, Y., Suzuki, Y., Fukushima, M., Ide, C
  • Journal Title: Restrative Neurology and Neuroscience Volume: 30 Pages: 127-136
• [Journal Article] Bone Marrow Stromal Cell Transplantation for Treatment of Sub-acute Spinal Cord Injury in the Rat (2010)
  • Author(s): Ide, C., Nakai, Y., Nakano, N., Seo, TB., Yamada, Y., Endo, K., Noda, T., Saito, F., Suzuki, Y., Fukushima, M,. Nakatani, T
  • Journal Title: Brain Res Volume: 1332 Pages: 32-47
• [Presentation] bFGF徐放化のあるヘパリン/アルギン酸ゲルを用いたラット急性期脊髄損傷に対する神経再生の評価 (2013)
  • Author(s): 平井達也、鈴木義久、石川奈美子、太田正佳、西田英高、田村勝利、井出千束、谷原正夫、鈴木康夫
  • Organizer: 第12回日本再生医療学会総会
  • Place of Presentation: パシフィコ横浜
  • Year and Date: 20130321-23
• [Presentation] 脊髄損傷の治療法の開発 (2012)
  • Author(s): 鈴木義久、石川奈美子、平井達也、月野暁彦、西林涼子、太田正佳
  • Organizer: 第21回日本形成外科学会基礎学術集会
  • Place of Presentation: ホテルリステル猪苗代
  • Year and Date: 20121004-05
• [Presentation] AMERICAN ASSOCIATION FOR THE SURGERY OF TRAUMA (2010)
  • Author(s): T,Nakatani,.M,Iwase,.F,Saito,. Y,Maeda,.H,Tsuchiya,.T,Ikeda,.T,Omura,.O,Iiji,.K,Matumoto,.A,Hirakawa,.Y,Urao,.Y,Suzuki,. M,Fukushima,. C,Ide
  • Organizer: ADMINISTRATION OF AUTOLOGOUS INCUBA TED BONE MARROW STROMALCELLS INTO CEREBROSPINASL FLUID IN SPINAL INJURY PATIENTS:A PILOT STUDY
  • Place of Presentation: BOSTON MARRIOTT COPLEY PLACE BOSTON,MA, U.S.A.
  • Year and Date: 20100922-25
• [Remarks]
  • URL: http://svso01.kitano-hp.or.jp/bportal/portal?PSML=PPage&Action=SBLogin