2012 Fiscal Year Final Research Report
Analyses of strengthening mechanisms of human dentin by UV
| Project/Area Number |
22390358
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
HAYASHI Mikako 大阪大学, 歯学研究科(研究院), 教授 (40271027)
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| Co-Investigator(Kenkyū-buntansha) |
IWAMI Yukiteru 大阪大学, 大学院・歯学研究科, 助教 (90303982)
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| Co-Investigator(Renkei-kenkyūsha) |
箕島 弘二 大阪大学, 工学 (系)研究科(研究院), 教授 (50174107)
斎藤 充 東京慈恵会医科大学, 医学部, 准教授 (50301528)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 保存修復学 / 象牙質 / 機械的強度 / 紫外線 / コラーゲン |
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| Research Abstract |
The strengthening effects of human dentin by UV irradiation were investigated with an aim of preventing tooth fracture. We found that a UV irradiation treatment with a wave length of 365 nm was significantly effective to improve the mechanical strengths of dentin with showing anisotolopy. The strengthening mechanism of dentin by UV was found to be the chemical changes in its type I collagen such as formation of new cross-links in relation with its typical amino acid such as proline.
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