2012 Fiscal Year Final Research Report
GENETIC AND ENVIRONMENTAL FACTORS INVOLVED IN SLEEP BRUXISM
| Project/Area Number |
22390363
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
YATANI Hirofumi 大阪大学, 歯学研究科, 教授 (80174530)
HAYAKAWA Kazuo 大阪大学, 医学系研究科, 教授 (70142594)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 顎口腔機能学 / 睡眠時ブラキシズム / 双生児研究 |
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| Research Abstract |
The objective was to reveal the importance of genetic and environmental factors involved in sleep bruxism. Twins were recruited from the Twin Mothers Club Japan through the Twin Research Center, Osaka University Graduate School of Medicine. Subjects consisted of 84 twins (42 twin pairs, mean age = 22.3± 6.8 yrs.). The total numbers of nocturnal electromyographic activities of the left temporal muscle were recorded with a portable automatic sleep bruxism analyzer. The recordings were carried out for three consecutive nights. The quantitative genetic statistics based on the structural equation modeling was carried out. The result of covariance structure analysis showed that the additive genetic effect was 0.42 and the unique environmental effect was 0.58. According to the result obtained from the present study genetic factors could be considered as a significant contributing factor for the initiation of sleep bruxism. However, the estimated environmental effect at 0.58 suggests the importance of individual evaluation of patients with sleep bruxism.
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[Remarks] The 14th Scientific Meeting of the Asian Academy of Craniomandibular Disorders (October 5-7, 2012, Taipei, Taiwanにて開催)における発表演題(学会発表欄(2))が,優秀ポスター発表賞(第3位)を受賞した
