2012 Fiscal Year Final Research Report
Maternal chewing prevents stress-induced learning impairment in pups
| Project/Area Number |
22390395
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Seijoh University |
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Principal Investigator |
KUBO Kin-ya 星城大学, リハビリテーション学部, 教授 (00329492)
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| Co-Investigator(Kenkyū-buntansha) |
IINUMA Mitsuo 朝日大学, 歯学部, 准教授 (70184364)
CHEN Huayue 岐阜大学, 医学研究科, 講師 (20273146)
ONOZUKA Minoru 神奈川歯科大学, 歯学部, 名誉教授 (90084780)
ICHIHASHI Yukiko 朝日大学, 歯学部, 助教 (70515634)
KARASAWA Nobuyuki 星城大学, リハビリテーション学部, 名誉教授
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| Project Period (FY) |
2010 – 2012
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| Keywords | 小児歯科学 |
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| Research Abstract |
Maternal stress induces developmental brain impairment, emotional abnormalities, and learning deficits in pups. Maternal chewing prevents the stress-induced increase in plasma corticosterone levels in dams, as well as neurodevelopmental disorders, anxiety-like behavior, and learning deficits in the pups. Maternal chewing is an effective stress-coping method for the dams to prevent learning deficits in pups.
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