2012 Fiscal Year Final Research Report
Investigation on the automation and speeding up ofmeasurement of the plasma IgG antibody titers against periodontopathic bacteria
| Project/Area Number |
22390397
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Periodontal dentistry
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| Research Institution | Okayama University |
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Principal Investigator |
TAKASHIBA Shogo 岡山大学, 大学院・医歯薬学総合研究科, 教授 (50226768)
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| Co-Investigator(Kenkyū-buntansha) |
MAEDA Hiroshi 岡山大学, 大学院・医歯薬学総合研究科, 准教授 (00274001)
OHARA Naoya 岡山大学, 大学院・医歯薬学総合研究科, 教授 (70223930)
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| Research Collaborator |
NOZOE Mikio サンスター株式会社
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| Project Period (FY) |
2010 – 2012
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| Keywords | 歯学 / 細菌 / 感染症 / 免疫学 / プロテオーム |
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| Research Abstract |
It is difficult to measure serum IgG antibody titers against periodontopathic bacteria stably and speedily. In this study, we havesucceeded to select antigens of Porphyromonas gingivalisfor effective serodiagnosis of periodontitis and synthesized 16 antigens. In addition, we confirmed the reaction against serum obtained from periodontal patients. Inthe future, we will identify antigens for effective serodiagnosis and establish the automatic diagnostic system.
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