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2012 Fiscal Year Final Research Report

The toxic substances as a factor of causing the region of a high risk of cancer incidencein China.

Research Project

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Project/Area Number 22401008
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Environmental impact assessment/Environmental policy
Research InstitutionPrefectural University of Kumamoto

Principal Investigator

ARIZONO Koji  熊本県立大学, 環境共生学部, 教授 (70128148)

Co-Investigator(Kenkyū-buntansha) WATANABE Chiho  東京大学, 医学系研究科 (70220902)
ISHIBASHI Hiroshi  尚絅大学, 短期大学部 (90403857)
YOSHIDA Yoshitoku  名古屋大学, 医学研究科 (90506635)
ISHIBASHI Yasuhiro  熊本県立大学, 環境共生学部 (00212928)
Project Period (FY) 2010 – 2012
Keywords環境影響評価 / 環境政策
Research Abstract

The environmental samples (living environment water considered to contain toxic substance) were collected from the region and several the provinces which have a high risk of cancer incidence, and were analyzed the concentration of various chemical substances based on the information on the industrial area in China. As a result, o,p’-DDT was detected. Therefore, the ecology impact evaluation was performed using the DNA microarray of medaka. On the other hand, environmental water and food (agricultural products and a marine product) contamination of metals study using ICP-MS and the immune-chromatography whichspecialized in cadmium were cooperated with China Hainan CDC. At the area which conducted metallic pollution investigation of the heavy metal (cadmium and lead). The local resident's health survey was performed with metal analysis. The lead pollution of the Hainan marine products was detected in 0.005-0.717mg/kg, and River contamination of cadmium was detected 0.100x10-3 - 0.648 mg/kg was detected.

  • Research Products

    (44 results)

All 2013 2012 2011 Other

All Journal Article (13 results) (of which Peer Reviewed: 13 results) Presentation (31 results)

  • [Journal Article] Development of a novel GC/MS database for the determination of additives for containers and packaging and its application to processed foods' analysis2013

    • Author(s)
      Nakashima S, Ji H,Ishitobi S, Yamagami T, Asai K, K, Kadokami K, Musuga M, Kawamura Y, Koga M, Shinohara R , Ishibashi H, Tominaga N, Arizono K
    • Journal Title

      Japanese Journal of Food Chemistry

      Volume: 12(1) Pages: 42-51

    • Peer Reviewed
  • [Journal Article] Theoretical estimation of measurement precision for materials in database of GC/MS2013

    • Author(s)
      Nakashima S, Ono Y, Yamagami T, Koga S, Shinohara R, Arizono K, Hayashi Y
    • Journal Title

      Environment and safety

      Volume: vol. 4(1) Pages: 3-8

    • Peer Reviewed
  • [Journal Article] Acute toxicity of 4-nonylphenol isomers to larval medaka Oryzias latipes2013

    • Author(s)
      Kobayashi J, Sun C, Ji H,Ishibash Y, Shinohara R, KogaM, Arizono K
    • Journal Title

      Environment and safety

      Volume: 4(1) Pages: 9-14

    • Peer Reviewed
  • [Journal Article] Uncertainty depended on standard solution preparation for water quality examination and influence on accuracy of quantitative analysis2012

    • Author(s)
      Tahara M, Nakashima S, Sugimoto N, Ariozno K, Nishimura T
    • Journal Title

      Journal of Japan Water Works Association

      Volume: Vol81 (5) Pages: 10-16

    • Peer Reviewed
  • [Journal Article] Toxicological effects of glyphosate formulation in Japanese medaka(Oryzas Latipes)2012

    • Author(s)
      Uchida M, Takumi, S, Tachikawa K, Yamauchi R, Goto Y, Matsusaki H,Nakamura H, Kagami Y, Kusano T, Arizono K
    • Journal Title

      The Journal of Toxicological. Sciences

      Volume: Vol. 37 (2) Pages: 245-254

    • Peer Reviewed
  • [Journal Article] Phytoremediation of various bisphenol derivatives by Portulaca oleraceacv2012

    • Author(s)
      Okuhata H, NinagawaM, TakemotoN, JiH, Miyasaka H, Ishibashi Y, Arizono K
    • Journal Title

      Bioengineerin

      Volume: Vol 115(1) Pages: 55-57

    • Peer Reviewed
  • [Journal Article] Evaluation of triclosan degradation process using pulse discharge in pure water (in Japanese).2012

    • Author(s)
      Matsuo H, Morodome A Sankoda K, Kobayashi J, Koga M, Ishibashi Y, Arizono K, Shinohara, R
    • Journal Title

      Environment and safety

      Volume: vol.3 Pages: 27-31

    • Peer Reviewed
  • [Journal Article] Removal of bisphenol A related compounds by Portulaca oleracea (in Japanese)2011

    • Author(s)
      Ninagawa M, Takemoto N, JiH, Miyasaka H, Okuhata H, Ishibashi Y, Arizono K
    • Journal Title

      Environment and safety

      Volume: vol. 2(1) Pages: 23-29

    • Peer Reviewed
  • [Journal Article] Study on GC/MS analytical methods for branced nonylphenol isomers, (in Japanese)2011

    • Author(s)
      Ji H, Kawakami S, Inokuchi A, Shinohara R, M. Koga, Uchiyama, T, Katase T, Arizono K
    • Journal Title

      Environment and safety

      Volume: vol. 2(1) Pages: 31-37

    • Peer Reviewed
  • [Journal Article] The applicability of GC/MS detection and quantification using a database for the determination of pesticides in river water, (in Japanese)2011

    • Author(s)
      Yamagami T, Nakashima S, Ono Y, Ishibashi Y, Arizono K, Kadokami K
    • Journal Title

      Environment and safety

      Volume: vol. 2(2) Pages: 159-169

    • Peer Reviewed
  • [Journal Article] Behavior of pharmaceuticals in waste water treatment plant in Japan2011

    • Author(s)
      Matsuo H, Sakamoto H, Arizono K, Shinohara R
    • Journal Title

      Bull Environ Contam Toxicol

      Volume: 87(1) Pages: 31-35

    • Peer Reviewed
  • [Journal Article] Gene expression analysis of Japanese medaka (Oryzias latipes) exposed to o,p'-DDT using DNA microarray2011

    • Author(s)
      Uchida M, Nakamura H, Kagami Y, Kusana T, Arizono K
    • Journal Title

      Organohalogen Compounds

      Volume: 73 Pages: 484-487

    • Peer Reviewed
  • [Journal Article] The Research on the Generation Control of Dioxines from the Small Incinerator2011

    • Author(s)
      Ishibashi Y, Arizono K, Nakamichi T, Takemoto N, Kai H, Shimase H, Takemasa T
    • Journal Title

      Organohalogen Compounds

      Volume: 73 Pages: 1788-1791

    • Peer Reviewed
  • [Presentation] Toxicity of triclosan and triclocarban in mysid crustacean2012

    • Author(s)
      Arizono K, Uchida M, Koga M
    • Place of Presentation
      Dioxin
    • Year and Date
      20120000
  • [Presentation] Functional analyses of the mysid ecdysteroid receptor: DNA binding ability, ligand-induced transactivation and in silico modeling.2012

    • Author(s)
      Hirano M, Ishibashi H, Kim EY Arizono K , Iwata H
    • Place of Presentation
      SETAC Asia Pacific
    • Year and Date
      20120000
  • [Presentation] (12) First results from a ring study of a new rapid alga test estimating chemical influence on algal growth.2012

    • Author(s)
      Katsumata M, Arizono K etc
    • Place of Presentation
      SETAC Asia Pacific
    • Year and Date
      20120000
  • [Presentation] Effects of PFOA and fluorotelomer alcohol on Caenorhabditis elegans reproduction.2012

    • Author(s)
      Tominaga N, Furukawa R, Yamashita S, Yamaguchi A, Arizono K
    • Place of Presentation
      SETAC Asia Pacific
    • Year and Date
      20120000
  • [Presentation] GC/MS Software and Database for Screening Analysis: Mechanism and Evaluation UsingRiver Water Samples.2012

    • Author(s)
      Nakashima S, Yamagami T, Ogawa Y, Kadokami K, Arizono K
    • Place of Presentation
      SETAC Asia Pacific
    • Year and Date
      20120000
  • [Presentation] Rapid analyticalmethod for surfactant in wastewater using biosensor.2012

    • Author(s)
      Oshima S, Takagi Y, Sawadaishi K, Kataoka C, Arizono K
    • Place of Presentation
      SETAC Asia Pacific
    • Year and Date
      20120000
  • [Presentation] Evaluation of ecological toxicity of glyphosate agrochemical components in Japanese medaka.2012

    • Author(s)
      Uchida M, Takumi S, Nakamura Y,Kagami Y, Kusano T, Arizono K
    • Place of Presentation
      SETAC Asia Pacific
    • Year and Date
      20120000
  • [Presentation] Miyasaka H, Removal of bisphenol A related compounds by Portulaca oleracearoot and horse radish peroxidase.2012

    • Author(s)
      Arizono K, Takemoto N, Okuhata H
    • Place of Presentation
      SETAC North America
    • Year and Date
      20120000
  • [Presentation] The Research on the Generation Control of Dioxines from the Small Incinerator.2011

    • Author(s)
      Ishibashi Y, Nakamichi T, Arizono K
    • Place of Presentation
      Dioxin
    • Year and Date
      20110000
  • [Presentation] Gene expression analysis of Japanese medaka exposed to o,p'-DDT using DNA microarray.2011

    • Author(s)
      Uchida M, Nakamura H, Kagami Y, Kusano T, Arizono K
    • Place of Presentation
      Dioxin
    • Year and Date
      20110000
  • [Presentation] Construction of Chemical Toxicity Prediction Model by Using Experiment Data2011

    • Author(s)
      Arizono K, Ji H
    • Organizer
      Mainly on Branched Nonylphenol Isomers
    • Place of Presentation
      SETAC North America
    • Year and Date
      20110000
  • [Presentation] 線虫C. elegansにおけるナノシリカの生体影響及び遺伝子発現変動解析

    • Author(s)
      井口綾子、有薗幸司 ,他9 名
    • Organizer
      第37回 日本トキシコロジー学会学術年会
  • [Presentation] グリホサート製剤がヒメダカにおよぼす影響

    • Author(s)
      内田雅也、有薗幸司 ,他6名
    • Organizer
      第37回 日本トキシコロジー学会学術年会
  • [Presentation] 最終処分場由来の浸出水中有機フッ素化合物のリスク評価

    • Author(s)
      有薗幸司、竹本直道、川上茂樹、内田雅也、吉嚇哲
    • Organizer
      第19回環境化学討論会
  • [Presentation] 下水処理場の処理過程におけるノニルフェノール異性体の挙動

    • Author(s)
      吉嚇哲、川上茂樹、竹本直道、内山武人、片瀬隆雄、有薗幸司
    • Organizer
      第19回 環境化学討論会
  • [Presentation] 沖縄本島の漁港底質中の有機スズ化合物濃度および他地域との比較

    • Author(s)
      桑原和子、有薗幸司 ,他8名
    • Organizer
      第19回 環境化学討論会
  • [Presentation] タイヤチップに対するユスリカを用いた毒性試験法の検討

    • Author(s)
      中川理緒、鑪迫典久、有薗幸司
    • Organizer
      第16回日本環境毒性学会・パイオアッセイ研究会
  • [Presentation] メダカDNAマイクロアレイを用いたグリホサート製剤の生体影響評価

    • Author(s)
      内田雅也、有薗幸司 ,他6名
    • Organizer
      第16回日本環境毒性学会・パイオアッセイ研究会
  • [Presentation] 熊本県における大豆、大豆製品のRoundup Ready Soybean 混入状況

    • Author(s)
      渡辺郁子、井口綾子、本田栄子、有薗幸司
    • Organizer
      第100回 日本食品衛生学会
  • [Presentation] ICP-MSによる飼料米鶏卵中重金属類の一斉分析

    • Author(s)
      上田亜紀、吉嚇哲、田崎幸美、高橋まどか、白土英樹、有薗幸司
    • Organizer
      第100回日本食品衛生学会
  • [Presentation] Effects of endogenous and xenobiotic compounds on DNA binding and transactivation ofthe crustacean ecdysteroid receptor.

    • Author(s)
      Ishibashi H, Arizono K and Iwata H
    • Organizer
      日本内分泌撹乱化学物質学会第13回研究発表会
  • [Presentation] 線虫をモデル生物としたナノシリカの生態影響評価

    • Author(s)
      井口綾子、有薗幸司
    • Organizer
      日本薬学会年会
  • [Presentation] 最終処分場由来浸出水のリスク評価-多元素分析からのアプローチ-

    • Author(s)
      竹本直道、吉嚇哲、石橋康弘、大場和彦、有薗幸司
    • Organizer
      第20回 環境化学討論会
  • [Presentation] 乳がんおよび良性乳腺症例における脂肪組織中の有機塩素系化合物レベル

    • Author(s)
      郡山千早、有薗幸司 ,他10名
    • Organizer
      第20回 環境化学討論会
  • [Presentation] 使用方法の異なるPPCPsをマーカーとして用いた河川水の生活排水等による汚濁パターンの分類法の開発

    • Author(s)
      三浦嘉仁、有薗幸司 ,他5名
    • Organizer
      第20回 環境化学討論会
  • [Presentation] 高電界パルスを用いた化学物質の初期発生影響評価法の開発-パルス印加およびタンパク合成阻害剤曝露によるメダカ卵の遺伝子発現変動の調査-

    • Author(s)
      富永伸明、山口明美 有薗幸司
    • Organizer
      日本内分泌撹乱化学物質学会第14回研究発表会
  • [Presentation] In vitro and in silico analyses of the interaction of environmental chemicals with the mysid ecdysteroid receptor

    • Author(s)
      Hirano M, ArizonoK, Iwata H
    • Organizer
      日本内分泌撹乱化学物質学会第14回研究発表会
  • [Presentation] アミDNAマイクロアレイを用いたDDTの生態影響評価

    • Author(s)
      内田雅也 有薗幸司 ,他6名
    • Organizer
      水環境学会九州支部会
  • [Presentation] 液体合成培地を用いた線虫のin vivo 評価系によるCuの影響評価

    • Author(s)
      荒巻愛世、富永伸明、有薗幸司
    • Organizer
      第17回日本環境毒性学会・パイオアッセイ研究会
  • [Presentation] Transactivation potencies of the Baikal Seal peroxisome proliferator-Activated receptor by brominated flame retardants

    • Author(s)
      Ishibashi H, Arizono K, Iwata H
    • Organizer
      日本内分泌撹乱化学物質学会第15回研究発表会
  • [Presentation] Life Cycle Assessment Evaluation of dairy farming by input-output balance.

    • Author(s)
      Kai H, Nakamichi T, Takemoto N, Kamohara S, Arizono K, Ishibashi Y

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Published: 2014-08-29   Modified: 2017-11-21  

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