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2012 Fiscal Year Final Research Report

Epidemiological study for identifying risk factors of esophageal adenocarcinoma in north China.

Research Project

  • PDF
Project/Area Number 22406021
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Public health/Health science
Research InstitutionNiigata University

Principal Investigator

AKAZAWA Kohei  新潟大学, 医歯学総合病院, 教授 (10175771)

Co-Investigator(Kenkyū-buntansha) TERAJIMA Kenshi  新潟大学, 医歯学総合病院, 准教授 (00377160)
WAKAI Toshifumi  新潟大学, 医歯学系, 教授 (50372470)
Project Period (FY) 2010 – 2012
Keywords疫学 / 国際保健学 / 健康管理 / 保健医療行政 / 地域保健 / 集団検診 / 医療情報学
Research Abstract

Purpose : A matched case-control study to clarify the risk factors of alcohol and tobacco intake on the development of esophageal adenocarcinoma was collected in Hebei Province of China. Multivariate conditional logistic regression analysis indicated that only alcohol consumption was a significant risk factor for esophageal adenocarcinoma. Additional analysis of the combination of amount and duration of alcohol consumption indicated that heavy drinkers (> 30 ml/day) had significantly higher ORs, irrespective of the duration of alcohol consumption. In conclusion, heavy alcohol consumption increases the risk for esophageal adenocarcinoma independent of the duration of such consumption.

  • Research Products

    (6 results)

All 2013 2012 2011 2010 2009

All Journal Article (5 results) (of which Peer Reviewed: 5 results) Presentation (1 results)

  • [Journal Article] Heavy alcohol intake is a risk factor for esophageal squamous cell carcinoma among middle-aged Chinese men : a case-control study and simulation2013

    • Author(s)
      Kumagai N, Akazawa K, Wakai T et al
    • Journal Title

      Molecular and Clinical Oncology

      Volume: (in press)

    • Peer Reviewed
  • [Journal Article] Association of nitrogen compounds in drinking water with incidence of esophageal squamous cell carcinoma in Shexian, China2012

    • Author(s)
      Zhang N, Yu C, Wen D, Chen J, Ling Y, Terajima K, Akazawa K, Shan B, Wang S
    • Journal Title

      Tohoku J Exp Med

      Volume: 226(1) Pages: 11-17

    • DOI

      DOI:10.1620/tjem.226.11

    • Peer Reviewed
  • [Journal Article] Alcohol consumption as a risk factor for esophageal adenocarcinoma in North China2011

    • Author(s)
      Chen J, Zhang N, Ling Y, Wakai T, He Y, Wei L, Wang S, Akazawa K
    • Journal Title

      Tohoku J Exp Med

      Volume: 224(1) Pages: 21-27

    • DOI

      DOI:10.1620/tjem.224.21

    • Peer Reviewed
  • [Journal Article] Clustering and Geographic Variation of Upper Gastrointestinal Cancers in a High-risk Region of Esophageal Cancer in Northern China2011

    • Author(s)
      Zhang N, Wen D, Shan B, Wang S, Zhang L, Wei L, Zou W, Kitsu K, Akazawa K
    • Journal Title

      Asian Pac J Cancer Prev

      Volume: 12(1) Pages: 193-198

    • URL

      http://www.apocpcontrol.org/page/apjcp_issues_view.php?pno=1558&gubun=p&s_search=&s_paper_vol=12&s_number33=1

    • Peer Reviewed
  • [Journal Article] Effect of the interaction between the amount and duration of alcohol consumption and tobacco smoking on the risk of esophageal cancer:A case-control study2010

    • Author(s)
      Chen J, Zhang N, Wakai T, Wei L, He Y, Kumagai N, Kitsu K, Wang S, Akazawa K
    • Journal Title

      Experimental and therapeutic medicine

      Volume: 1(6) Pages: 991-997

    • DOI

      DOI:10.3892/etm.2010.152

    • Peer Reviewed
  • [Presentation] 発癌リスク因子探索のための症例対象研究とその統計学的な性質の解明2009

    • Author(s)
      陳君
    • Organizer
      第29回医療情報学連合大会
    • Place of Presentation
      広島国際会議場
    • Year and Date
      2009-11-22

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Published: 2014-08-29  

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