2012 Fiscal Year Final Research Report
Development of medical technology assessment methodology based on Bayesian statistics
| Project/Area Number |
22500257
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Statistical science
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Research Collaborator |
DAIMON Takashi 兵庫医科大学, 医学部, 准教授 (40372156)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 医薬生物・ゲノム統計解析 / ベイズ統計学 |
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| Research Abstract |
Since 1950s in which the methodology of clinical trials was established, significance tests and estimation have dominated as standard approaches. This approach is called frequentist approach. In recent years, Bayesian statistics have been applied to compl ex stati stical modeling in biomedical field and several approaches to study design and sequential monitoring have been proposed mainly in cancer clinical trials . We developed new design for exploratory clinical trials based on Bayesian approach.
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