2012 Fiscal Year Final Research Report
Morphological classification and synaptic connectivity analysis of retinal neurons by three-dimensional reconstruction
| Project/Area Number |
22500317
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Nerve anatomy/Neuropathology
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| Research Institution | Hyogo Medical University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Keywords | ニューロン / 網膜 / 神経回路 / シナプス / マウス / サル / 電子顕微鏡 |
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| Research Abstract |
(1) We analyzed the allocations of synaptic contacts in microcircuits from rods via rod bipolar to AII amacrine cells, the gap junctions between AII amacrine and ON cone bipolar cells, and the synaptic contacts from OFF bipolar to OFF ganglion cells in the mouse retina.We also made a map of 30 ganglion cells. (2) We made two maps of cones and rods in the fovea (Eccentricity: 0.25～0.45mm) and the peri-fovea (3.06～3.22mm) and discovered thedirect chemical synaptic pathway from rods to OFF cone bipolar cells in the monkey retina.
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