2012 Fiscal Year Final Research Report
Freezing and festinating : zebrafish model shed light onpathophysiology of gait disturbances
| Project/Area Number |
22500358
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Neurophysiology and muscle physiology
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| Research Institution | Kumamoto University |
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Principal Investigator |
SAITOH Kazuya 熊本大学, 教育学部, 准教授 (20301997)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 姿勢 / 運動制御 |
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| Research Abstract |
Locomotion in our daily life is transferred to steering,elimination of locomotion etc., depending on surroundings. Our aim is to elucidatepathophysiology of gait disturbances in Parkinson’s disease by studying the neuralmechanism of this conversion. Brain activities were successfully recorded from adultMedaka fish during fictive locomotion. We also tried to make an isolated brain-eye-spinalcord preparation using adult Medaka fish as an advanced experimental model. Decline inretinal function still remain to be solved.
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[Journal Article] Identification andcharacterization of an insular auditory fieldinmic2011
Author(s)
Sawatari, H., Tanaka, Y., Takemoto, M.,Nishimura, M., Hasegawa, K., Saitoh, K.,and Song, W-J
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Journal Title
European Journal ofNeuroscience
Volume: 34
Pages: 1944-1952
Peer Reviewed
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