2012 Fiscal Year Final Research Report
Development of wearable artificial endocrine pancreas with needle-typeglucose sensor and closed-loop subcutaneous insulin infusionalgorithm
| Project/Area Number |
22500411
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Kumamoto University |
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Principal Investigator |
SHIMODA Seiya 熊本大学, 大学院・生命科学研究部, 講師 (60398203)
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| Co-Investigator(Kenkyū-buntansha) |
FURUKAWA Noboru 熊本大学, 大学院・生命科学研究部, 准教授 (90335795)
ARAKI Eiichi 熊本大学, 大学院・生命科学研究部, 教授 (10253733)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 人工臓器工学 / 再生医工学 |
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| Research Abstract |
We applied the artificial endocrine pancreas (AEP) system with PIsensor and a closed-loop subcutaneous insulin infusion algorithm developed for glycemiccontrol in diabetic dogs. The use of the WAEP system resulted in excellent glycemic controlafter a meal load of 80 kcal/kg (post-challenge blood glucose levels: from 70.2 to 181.8mg/dL), without any hypoglycemia. Thus, the new AEP with PI sensor and a closed-loopsubcutaneous insulin infusion algorithm developed is potentially suitable for clinicalapplication.
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Research Products
(7 results)
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[Book]2012
Author(s)
西田健朗,下田誠也
Total Pages
75-84
Publisher
社団法人日本人工臓器学会
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