2012 Fiscal Year Final Research Report
Imaging of oxidant stress in brain ischemia using an electromagnetic horn type ESR spectrometer
| Project/Area Number |
22500412
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Oita University |
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Principal Investigator |
KAMIDA Tohru 大分大学, 医学部脳神経外科, 講師 (90315333)
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| Co-Investigator(Kenkyū-buntansha) |
KOBAYASHI Tadashi (30100936)
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| Project Period (FY) |
2009 – 2012
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| Keywords | 医用 / 生体画像 |
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| Research Abstract |
Imaging of a free radical in the living body is useful at diagnosis of the disease of oxidant stress origin, etc. In order to perform ESR measurement of a living specimen in a status epilepticus and a brain tumor models, L-band electromagnetic horn type ESR spectrometer was developed, and compared with the conventional loop gap resonator. Although ESR measurement was completed in each model at the latter, it was difficult for a low sensitivity in the former. Combining Q-band electromagnetic horn type ESR spectrometer with a three-dimensional local ESR signal detecting ESR imaging spectrometer was devised as a remedy.
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Research Products
(6 results)
