2012 Fiscal Year Final Research Report
To elucidate effects of a low-protein diet under molecular levels, aiming at constructing the nutrition education.
| Project/Area Number |
22500650
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | Kagoshima Prefectural College |
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Principal Investigator |
ARIMURA Emi 鹿児島県立短期大学, 生活科学科, 助教 (40552964)
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| Co-Investigator(Kenkyū-buntansha) |
HORIUCHI Masahisa 鹿児島大学, 医歯(薬)学総合研究科, 教授 (50264403)
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| Co-Investigator(Renkei-kenkyūsha) |
KAWAGUCHI Hiroaki 鹿児島大学, 獣医学部, 准教授 (60325777)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 栄養指導 / 食事療法 / 糖尿病 / 糖尿病腎症 / 食事たんぱく質 / 動物モデル / インスリン分泌不全 / レプチン受容体 |
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| Research Abstract |
Patients with diabetic nephropathy (DN) is increased remarkably, leading to the increased number of patients with dialysis as a primary cause. Diet therapy for diabetes is high-protein diet, leading to restriction of carbohydrate. Thus, the increased numbers of DN might be related to the diet therapy. We examined how dietary protein contents affect renal manifestations and glucose levels under diabetes conditions. Under the same contentof energy and fat, a diet composed of low-protein and high-carbohydrate improved more on not only the renal manifestations but also the carbohydrate metabolism, compared to a diet composed of high-protein and low-carbohydrate.
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