2012 Fiscal Year Final Research Report
Development of an osteoporosis prevention program involving metabolic syndrome correction in middle-aged to elderly females
| Project/Area Number |
22500671
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | Okayama Prefectural University |
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Principal Investigator |
KUBOTA Megumi 岡山県立大学, 保健福祉学部, 准教授 (80254564)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 中高年女性 / 肥満 / メタボリックシンドローム / 骨密度 |
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| Research Abstract |
The subjects consisted of 83 female residents who had been continuously investigated. In the latently obese group, the heel bone mineral density and leptin level were significantly higher than in the thin and normal groups, as previously reported, whereas the E2 level was significantly lower. These results suggest that Ca absorption in the intestinal tract is genetically influenced in thin/normal middle-aged females, whereas leptin in adipose cells contributes to the maintenance of the bone mineral density in latently obese/obese middle-aged to elderly females with a high percent body fat.
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