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2012 Fiscal Year Final Research Report

Evaluation and application of food components, which prevent metabolic syndrome

Research Project

  • PDF
Project/Area Number 22500757
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Eating habits, studies on eating habits
Research InstitutionThe Open University of Japan (2011-2012)
Nara Women's University (2010)

Principal Investigator

KOJO Shosuke  放送大学, 教養学部, 教授 (10108988)

Co-Investigator(Kenkyū-buntansha) ICHI Ikuyo  お茶の水女子大学, その他の部局等, 教授 (50403316)
Project Period (FY) 2010 – 2012
Keywords酸化ストレス / 糖尿病 / 動脈硬化 / 生活習慣病 / セラミド
Research Abstract

In the development of metabolic syndrome, lipid metabolism plays a key role. Especially we demonstrated an important role of ceramide. Nobiletin found in Citrus depressaof the citrus caused favorable effect on lipid metabolism to prevent metabolic syndrome in rats. In future it is important to find such food factors, which affect lipid metabolism.

  • Research Products

    (17 results)

All 2012 2011 2010 Other

All Journal Article (5 results) (of which Peer Reviewed: 5 results) Presentation (7 results) Book (4 results) Remarks (1 results)

  • [Journal Article] The role of Kupffer cells in carbon tetrachloride intoxication in mice2012

    • Author(s)
      K. Kiso, S. Ueno, M. Fukuda, I. Ichi, K. Kobayashi, T. Sakai, K. Fukui, and S. Kojo
    • Journal Title

      Biol. Pharm. Bull

      Volume: 35 Pages: 980-983

    • Peer Reviewed
  • [Journal Article] Oxygen is the key factor associated with the difference between in vivo and in vitro effects of antioxidants2012

    • Author(s)
      S. Kojo
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 109, No. 30 Pages: E2028

    • DOI

      doi:10.1073/pnas.1205916109

    • Peer Reviewed
  • [Journal Article] Increase in plasma ceramide levels via secretory sphingomyelinase activity in streptozotocin-induced diabetic rats2011

    • Author(s)
      K. Kobayashi, I. Ichi, T. Nakagawa, C. Kamikawa, Y. Kitamura, E. Koga, Y. Washino, Y. Hoshinaga, and S. Kojo
    • Journal Title

      Med. Chem. Commun

      Volume: 2 Pages: 536-541

    • Peer Reviewed
  • [Journal Article] Y. Kitamura, Y. Washino, E. Koga, A. Ito, M. Kawagoe, C. Nakazaki, K. Kiso, I. Ichi, T. Matsura, and S. Kojo2010

    • Author(s)
      Oxidative stress in the ischemic and non-ischemic parts of the rat liver after two-thirds ischemia/reperfusion
    • Journal Title

      Biosci. Biotechnol. Biochem

      Volume: 74 Pages: 979-983

    • Peer Reviewed
  • [Journal Article] Effect of nobiletin on lipid metabolism in rats2010

    • Author(s)
      E. Nagata, I. Ichi, R. Kataoka, M. Matsushima, N. Adachi, Y. Kitamura, T. Sasaki, and S. Kojo
    • Journal Title

      J. Health Sci

      Volume: 56 Pages: 705-711

    • Peer Reviewed
  • [Presentation] 四塩化炭素中毒における Kupffer 細胞による肝炎拡大機構2012

    • Author(s)
      木曽かおり、上野聡子、福田麻菜、市 育代、小林慧子、坂井隆志、福井 清、小城勝相
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-16
  • [Presentation] 肝臓での酸化ストレスによって起こること2012

    • Author(s)
      市 育代、小城勝相
    • Organizer
      日本家政学会第64回大会
    • Place of Presentation
      大阪
    • Year and Date
      2012-05-12
  • [Presentation] 生体内の酸化ストレス評価への化学的アプローチ2012

    • Author(s)
      小城勝相
    • Organizer
      第45回日本通風・核酸代謝学会教育講演
    • Place of Presentation
      奈良
    • Year and Date
      2012-02-16
  • [Presentation] 糖尿病におけるセラミド代謝の変化2011

    • Author(s)
      市育代、小城勝相
    • Organizer
      日本家政学会第63回大会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-29
  • [Presentation] ビタミンCの働きと活性酸素2010

    • Author(s)
      小城勝相
    • Organizer
      日本ビタミン学会市民公開講座「私たちの健康増進とビタミン、サプリメント」
    • Place of Presentation
      福岡
    • Year and Date
      2010-11-06
  • [Presentation] 肝臓の虚血・再灌流における酸化ストレス2010

    • Author(s)
      小城勝相、北村佑子、鷲野由紀子、古賀枝里子、中崎千尋、木曽かおり、松浦達也、市 育代
    • Organizer
      第63回日本酸化ストレス学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2010-06-24
  • [Presentation] ラットでのプロポリスによる体脂肪減少と脂質代謝改善の機構2010

    • Author(s)
      小城勝相
    • Organizer
      日本家政学会第62回大会
    • Place of Presentation
      広島
    • Year and Date
      2010-05-29
  • [Book] ビタミン関係の記述、岩波生物学辞典第5 版2012

    • Author(s)
      小城勝相
    • Publisher
      岩波書店
  • [Book] 放送大学印刷教材『改訂版 食と健康』「第1 章 食品の機能とその理解のために(小城勝相)」「第5 章 ビタミンとミネラル(小城勝相)」「第9 章 生体内酸化(小城勝相)」2012

    • Author(s)
      小城勝相、清水誠
    • Total Pages
      9-27、75-102、151-167
    • Publisher
      放送大学教育振興会
  • [Book] ビタミン C に関する記述『ビタミンの新栄養学』2012

    • Author(s)
      市 育代、小城勝相、柴田克己・福渡 努
    • Total Pages
      41 、62-63 、91-93 、128-129、158-159、173-174
    • Publisher
      講談社
  • [Book] Antioxidants as biomarkers of oxidative stress, In Biomarkers for Antioxidant Defense and Oxidative Damage: Principles and Practical Applications2010

    • Author(s)
      I. Ichi, and S. Kojo, G. Aldini, K.-J. Yeum, E. Niki, and R. M. Russell
    • Total Pages
      35-49
    • Publisher
      Wiley-Blackwell, Iowa, USA
  • [Remarks]

    • URL

      https://act.ouj.ac.jp/researcher/detail/?id=150

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Published: 2014-08-29  

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