An investigation on senescence regulation by trace elements: A trial of zinc nutriomics

2012 Fiscal Year Final Research Report

• Project/Area Number: 22500772
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Eating habits, studies on eating habits
• Research Institution: Seitoku University
• Principal Investigator: YOKOI Katsuhiko 聖徳大学, 人間栄養学部, 教授 (10200883)
• Co-Investigator(Kenkyū-buntansha): KONOMI Aki 帝京平成大学, 健康メディカル学部, 講師 (40529658)
• Project Period (FY): 2010 – 2012
• Keywords: 食と栄養 / 老化 / 微量元素 / 亜鉛

Research Abstract

Since the Japanese society has already faced advanced population ageing, we investigated a possibility of senescence regulation by trace elements, especially zinc. Zinc-deficient rats revealed alopecia and a decreased body weight gain and retroperitoneal

Research Products

• [Journal Article] 摂取不足が問題になる必須微量元素-特に、亜鉛と鉄を中心に- (2013)
  • Author(s): 横井克彦
  • Journal Title: Foods & Food Ingredients J. Jpn Volume: 218(1):5-11
  • Peer Reviewed
• [Journal Article] 成年女子の"貧血のない鉄欠乏症"における亜鉛値の一考察 (2011)
  • Author(s): 澤田孝子, 許斐亜紀, 横井克彦
  • Journal Title: 微量栄養素研究Trace Nutrients Research Volume: 28:84-88
  • Peer Reviewed
• [Journal Article] 連載・微量元素をめぐる動向(7)鉄:鉄の栄養特性と毒性 (2011)
  • Author(s): 横井克彦
  • Journal Title: ならびに利用と規制 食品衛生研究 Volume: 61(4):23-33
  • Peer Reviewed
• [Journal Article] Comparison of a modified hemoglobin regeneration efficiency method with a slope-ratio assay in measuring relative bioavailability of cocoa powder iron using rats (2011)
  • Author(s): Yokoi K., Konomi A., Otagi M
  • Journal Title: Biol Trace Elem Res Volume: 143(2):1103-1109
  • DOI: DOI:10.1007/s12011-010-8953-1
  • Peer Reviewed
• [Journal Article] 微量栄養素の摂取基準運用に関する留意点-法と科学に基づく業務の遂行- (2010)
  • Author(s): 横井克彦
  • Journal Title: 日本栄養士会雑誌 Volume: 53(10):4-15
  • Peer Reviewed
• [Presentation] 数学的方法による鉄の必要量の推定と食事摂取基準との比較パネルディスカッション 1「栄養学的見地から見た微量元素の功罪」 (2012)
  • Author(s): 横井克彦
  • Organizer: 第23回日本微量元素学会大会
  • Place of Presentation: 東京都 砂防会館シェーンバッハ・サボー
  • Year and Date: 2012-07-05
• [Presentation] 亜鉛欠乏および摂取制限が肝臓中タンパク質の発現に及ぼす影響 (2011)
  • Author(s): 横井 克彦、許斐 亜紀
  • Organizer: 第22回日本微量元素学会大会
  • Place of Presentation: 京都市 京都テルサ/京都府民総合交流プラザ
  • Year and Date: 2011-07-01
• [Presentation] 成年女子の"貧血のない鉄欠乏症"における亜鉛値の一考察 (2011)
  • Author(s): 澤田孝子、許斐亜紀、横井克彦
  • Organizer: 第28回日本微量栄養素学会学術集会
  • Place of Presentation: 京都市 京都リサーチパーク
  • Year and Date: 2011-06-11
• [Presentation] Effect of zinc deficiency on hepatic protein expression patterns in rats (2011)
  • Author(s): Yokoi K, Konomi A
  • Organizer: Minisymposium: Zinc presented at the Experimental Biology 2011
  • Place of Presentation: Washington Convention Center, Washington, DC, USA
  • Year and Date: 2011-04-11
• [Presentation] Zinc deficiency and liver protein expression in rats. Minisymposium 2: Zinc and Selenium (2010)
  • Author(s): Katsuhiko Yokoi, Aki Konomi
  • Organizer: International Society For Trace Element Research In Humans (ISTERH), Nineth International Conference
  • Place of Presentation: Rixos Premium Hotel, Belek, Turkey
  • Year and Date: 2010-10-21
• [Book] 鉄と亜鉛と銅, ビタミン・ミネラルの科学 (2011)
  • Author(s): 横井克彦, 五十嵐脩、江指隆年
  • Total Pages: 123-129
  • Publisher: 東京:朝倉書店