2012 Fiscal Year Final Research Report
Development of molecular targeting drugs that can regulate IL-10 functions
| Project/Area Number |
22501022
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Tumor immunology
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| Research Institution | Chiba University |
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Principal Investigator |
TAMURA Yutaka 千葉大学, 大学院・医学研究院, 准教授 (50263174)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 分子標的薬 / 悪性黒色腫 / IL-10 |
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| Research Abstract |
The malignant melanoma has highest malignancy in skin cancer. We aimed at the development of the new cure of the malignant melanoma. We constructed molecular target medicine with the next property: the noninvasive identification method to let deliver and accumulate molecular target medicine (IL-10 decoy which targeted IL-10) selectively and perform a malignant melanoma, the hyperthermia treatment with the release of IL-10 decoy containing it.
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Research Products
(11 results)
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[Journal Article] Preparation andcharacterization ofphospholipid-conjugated indocyanine green as a near-infrared probe2012
Author(s)
Suganami A, Toyota T, Okazaki S, Saito K, Miyamoto K, Akutsu Y, Kawahira H, Aoki A, Muraki Y, Madono T, Hayashi H, Matsubara H, Omatsu T, Shirasawa H, Tamura Y
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Journal Title
Bioorg Med Chem Lett
Volume: 22(24)
Pages: 7481-5
DOI
Peer Reviewed
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