2012 Fiscal Year Final Research Report
Induced Signal Transduction by Interaction between Nano-sized polymer Aggregates and Plasma Membrane of Cells
| Project/Area Number |
22510120
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Nanomaterials/Nanobioscience
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| Research Institution | Osaka University |
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Principal Investigator |
NISHIKAWA Takehiro 大阪大学, 大学院・情報科学研究科, 特別科学研究員 (40281836)
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| Project Period (FY) |
2010 – 2012
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| Keywords | ナノバイオ / ナノ材料 / 生体機能利用 |
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| Research Abstract |
n our research project supported by Grant-in-Aid for Scientific Research (C) (22510120), we studied how the expression level and phosphorylation of endothelial nitric oxide synthase (eNOS) are influenced when nanoparticles of amphiphilic polymer are endocytosed into vascular endothelial cells. We experimentally demonstrated that cellular uptake of the synthetic nanoparticles of polysiloxane can be processed assignals and result in the enhanced cellular responses (nitric oxide release). 交付決定額
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Research Products
(16 results)
