Molecular mechanisms of anhydrobiosis in the terrestrial cyanobacterium

2012 Fiscal Year Final Research Report

• Project/Area Number: 22510227
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Living organism molecular science
• Research Institution: Kanazawa University
• Principal Investigator: SAKAMOTO Toshio 金沢大学, 自然システム学系, 准教授 (70324069)
• Co-Investigator(Renkei-kenkyūsha): MATSUGO Seiichi 金沢大学, 自然システム学系, 教授 (30148126)
• Project Period (FY): 2010 – 2012
• Keywords: 生理活性物質 / 極限環境生物 / 抗酸化 / 紫外線

Research Abstract

Mycosporine-like amino acids (MAAs) are water-soluble pigments that absorb UV radiation of 280 to 340 nm. In this study, novel MAAs were purified from the terrestrial cyanobacterium Nostoc commune, and their chemical structures were characterized. These unique glycosylated MAAs have multiple roles as a UV protectant and an antioxidant relevant to anhydrobiosis in this organism. Moreover, glycosylated MAA patterns could be a feasible chemotaxonomic marker for the characterization of the morphologically indistinguishable N. commune.

Research Products

• [Journal Article] The cyanobacterial UV-absorbingpigment scytonemin displays radicalscavenging activity. (2012)
  • Author(s): Matsui, K., Nazifi, E., Hirai, Y., Wada, N., Matsugo, S. and Sakamoto, T
  • Journal Title: J. Gen. App. Microbiol Volume: 58 Pages: 137-144
  • DOI: DOI:10.2323/jgam.58.137
  • Peer Reviewed
• [Journal Article] Molecular genetic and chemotaxonomic characterization of the terrestrial cyanobacterium Nostoc commune and its neighboring species (2012)
  • Author(s): Arima, H., Horiguchi, N., Takaichi, S., Kofuji, R., Ishida, K., Wada, K. and Sakamoto, T
  • Journal Title: FEMS Microbiol. Ecol Volume: 79 Pages: 34-45
  • DOI: DOI:10.1111/j.1574-6941.2011.01195.x
  • Peer Reviewed
• [Journal Article] Novel glycosylated mycosporine-like amino acids with radical scavenging activity from the cyanobacterium Nostoc commune (2011)
  • Author(s): Matsui, K., Nazifi, E., Kunita, S., Wada, N., Matsugo, S. and Sakamoto, T.
  • Journal Title: Journal of Photochemistry and Photobiology B: Biology Volume: 105 Pages: 81-89
  • DOI: DOI:10.1016/j.jphotobiol.2011.07.003
  • Peer Reviewed
• [Journal Article] The extracellular-matrix-retaining cyanobacterium Nostoc verrucosumaccumulates trehalose, but is sensitive to desiccation. (2011)
  • Author(s): Sakamoto, T., Kumihashi, K., Kunita, S., Masaura, T., Inoue-Sakamoto, K. and Yamaguchi, M
  • Journal Title: FEMS Microbiol. Ecol Volume: 77 Pages: 385-394
  • DOI: DOI:10.1111/j.1574-6941.2011.01114.x
  • Peer Reviewed
• [Presentation] ラン藻の作る細胞外多糖の生理的機能 (2012)
  • Author(s): 坂本敏夫
  • Organizer: 日本植物学会第76回大会
  • Place of Presentation: 兵庫県立大学・書写キャンパス(兵庫県)
  • Year and Date: 20120915-17
• [Presentation] Glycosylated mycosporine-like amino acids from the terrestrial cyanobacterium Nostoc commune (2012)
  • Author(s): Toshio Sakamoto
  • Organizer: 14th International Symposium on Phototrophic Prokaryotes
  • Place of Presentation: Porto Palacio Congress Hotel & Spa, Porto, Portugal.
  • Year and Date: 20120805-10
• [Presentation] Characterization of a novel glycosylated mycosporine-like amino acid purified from the terrestrial cyanobacterium Nostoc commune (2012)
  • Author(s): Ehsan Nazifi
  • Organizer: 日本藻類学会第36回大会
  • Place of Presentation: 北海道大学学術交流会館(北海道)
  • Year and Date: 20120713-15
• [Presentation] 陸棲ラン藻Nostoc communeにおけるマイコスポリン様アミノ酸の多様性 (2012)
  • Author(s): 山場みなみ
  • Organizer: 日本藻類学会第36回大会
  • Place of Presentation: 北海道大学学術交流会館(北海道)
  • Year and Date: 20120713-15
• [Presentation] 水棲ラン藻Nostoc verrucosum(アシツキ)の紫外線吸収色素 (2012)
  • Author(s): 辻智栄理
  • Organizer: 日本藻類学会第36回大会
  • Place of Presentation: 北海道大学学術交流会館(北海道)
  • Year and Date: 20120713-15
• [Presentation] 陸棲シアノバクテリア(イシクラゲ)の細胞外多糖とその生理機能 (2012)
  • Author(s): 坂本敏夫
  • Organizer: 第4回 高資源循環ポリマーセンターシンポジウム(招待講演)
  • Place of Presentation: 北陸先端科学技術大学院大学・品川キャンパス(東京都)
  • Year and Date: 20120313-14
• [Presentation] 陸棲ラン藻Nostoc communeのもつ紫外線吸収色素と遺伝子型の多様性 (2011)
  • Author(s): 山場みなみ
  • Organizer: ラン藻の分子生物学2011
  • Place of Presentation: かずさアカデミアホール(千葉県)
  • Year and Date: 20111202-03
• [Presentation] 水棲ラン藻Nostoc verrucosum(アシツキ)の紫外線吸収色素 (2011)
  • Author(s): 辻智栄理
  • Organizer: ラン藻の分子生物学2011
  • Place of Presentation: かずさアカデミアホール(千葉県)
  • Year and Date: 20111202-03
• [Presentation] Novel glycosylated mycosporine-like amino acids with radical scavenging activity from the cyanobacterium Nostoc commune (2011)
  • Author(s): Ehsan Nazifi
  • Organizer: ラン藻の分子生物学2011
  • Place of Presentation: かずさアカデミアホール(千葉県)
  • Year and Date: 20111202-03
• [Presentation] 陸棲ラン藻Nostoc commune (和名:イシクラゲ)における紫外線吸収色素と抗酸化活性 (2011)
  • Author(s): 松井慧
  • Organizer: 日本藻類学会第35回大会
  • Place of Presentation: 富山大学(富山県)
  • Year and Date: 20110327-28
• [Presentation] Nostoc属ラン藻のストレス耐性と細胞外多糖の解析 (2011)
  • Author(s): 丹治康範
  • Organizer: 日本藻類学会第35回大会
  • Place of Presentation: 富山大学(富山県)
  • Year and Date: 20110327-28
• [Presentation] 陸棲ラン藻の起源を探る (2011)
  • Author(s): 坂本敏夫
  • Organizer: ラン藻ゲノム研究交流会
  • Place of Presentation: 東京大学・駒場キャンパス(東京都)
  • Year and Date: 2011-07-02
• [Presentation] Deactivation of photosynthesis and accumulation of trehalose in response to desiccation and salt stress in the terrestrial cyanobacterium Nostoc commune (2010)
  • Author(s): Toshio Sakamoto
  • Organizer: The 15th International Congress on Photosynthesis
  • Place of Presentation: Beijing Friendship Hotel, Beijing, China.
  • Year and Date: 20100822-27
• [Remarks] 「金沢大学理工学域 自然システム学類生物学コース 生命機構講座 坂本研究室」
  • URL: http://photon.w3.kanazawa-u.ac.jp/