2012 Fiscal Year Final Research Report
Catalysis in Metal Array Fabricated by Self-Assembly of Metalated Amino Acids/Peptides
| Project/Area Number |
22550099
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Kyoto University |
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Principal Investigator |
TAKAYA Hikaru 京都大学, 化学研究所, 准教授 (50304035)
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| Co-Investigator(Kenkyū-buntansha) |
ISOZAKI Katsuhiro 京都大学, 化学研究所, 助教 (30455274)
SEIKE Hirofumi 京都大学, 化学研究所, 特任研究員 (20523161)
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| Project Period (FY) |
2010 – 2012
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| Keywords | メタル化アミノ酸 / メタル化ペプチド / ペプチド科学 / 超分子触媒 |
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| Research Abstract |
Precisely-controlled metal array fabrication was accomplished through self-assembly of metalated amino acids and related peptides in which functional transition-metal complexes conjugate to the α-side chain of amino acids. The chemically and physically robust Pd- Pt- and Ru-complex-bound amino acids gave nanometer-scale controlled metal array fabricated by ultrasound-induced gelation or micelle formation. Control of metal sequence was accomplished by condensation of these Pd- and Pt-bound amino acids by chronological ordering of the amino acid condensation. Supramolecular-based self-assembly of Pd- and Pt-bound dipeptides also gave nanometer-scale regulated array of Pd- and Pt-complexes. The resulting Pd-, Pt- and Ru-array acts as efficient recyclable supramolecularcatalyst in aqueous conditions toward various types of organic reactions such as alkyne transformation, cross-coupling reactions, and oxidations of alcohols.
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