2012 Fiscal Year Final Research Report
Studies on biological control theory for analysis and synthesis of molecule attractors fluctuated by intrinsic noise
| Project/Area Number |
22560454
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Control engineering
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| Research Institution | Waseda University |
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Principal Investigator |
UCHIDA Kenko 早稲田大学, 理工学術院, 教授 (80063808)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 制御理論 / 生物制御 / アトラクター制御 |
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| Research Abstract |
By using mathematical models and investigating the control mechnism that generates biological rhythms against intrinsic noises, which is the objective of this study, we have the following results: (1) We proposed evaluation measures of amplitude and periodicity fluctuations of oscillatory attractors by intrinsic noise; we characterized (2) the parameter set and (3) the feedback structure that make the rhythm more robust against intrinsic noise ; (4) we built the mathematical model that presents simultaneously the temperature compensation and the temperature entrainment when intrinsic noise can be neglected.
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[Journal Article] Discovery of a novel type of autophagy targeting RNA2013
Author(s)
Y.Fujiwara, A.Furuta, H.Kikuchi, S.Aizawa, Y.Hatanaka, C.Konya, K.Uchida, A.Yoshimura, Y.Tamai, K.Wada, T.Kabuta
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Journal Title
Autophagy
Volume: Vol.9:3
Pages: 403-409
Peer Reviewed
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