Elucidation of protein modification system with related ubiquitin protein, RUB/Nedd8, in Arabidopsis

2012 Fiscal Year Final Research Report

• Project/Area Number: 22570056
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Plant molecular biology/Plant physiology
• Research Institution: Japan Atomic Energy Agency
• Principal Investigator: OONO Yutaka 独立行政法人日本原子力研究開発機構, 量子ビーム応用研究部門, 研究主幹 (30343940)
• Co-Investigator(Renkei-kenkyūsha): SAKAMOTO Ayako 独立行政法人日本原子力研究開発機構, 量子ビーム応用研究部門, 研究主幹 (00354960) ; SATO Katsuya 独立行政法人日本原子力研究開発機構, 量子ビーム応用研究部門, 研究副主幹 (90370402) ; CHIBA Tomoki 筑波大学, 生命環境科学研究科, 教授 (00311423)
• Project Period (FY): 2010 – 2012
• Keywords: 植物分子機能 / ユビキチン様タンパク質

Research Abstract

Protein modification system by a small protein, RUB/Nedd8, was elucidated with taking into account functional relationship of a novel auxin-signaling factor, SMAP1. Genetic analyses and inhibitor examination revealed that SMAP1 is involved in plant growth and development via its interaction with components associated with RUB/Nedd8 modification.

Research Products

• [Journal Article] SMALL ACIDIC PROTEIN 1 acts with RUB modification components the COP9 signalosome and AXR1, to regulate growth and development of Arabidopsis thaliana. (2012)
  • Author(s): Nakasone A, Fujiwara M, Fukao Y, Biswas KK, Rahman A, Kawai-Yamada M, Narumi I, Uchimiya H, Oono Y.
  • Journal Title: Plant Physiology Volume: 160 Pages: 93-105
  • DOI: doi:10.1104/pp.111.188409
  • Peer Reviewed
• [Journal Article] Genetic interaction between COP9 signalosome and SMAP1 that function in the 2,4-D response in Arabidopsis. (2012)
  • Author(s): Oono Y, Narumi I
  • Journal Title: JAEA-Review Volume: 2011-043 Pages: 99
  • Peer Reviewed
• [Journal Article] New insights to auxin signaling through the use of small molecules. (2011)
  • Author(s): Biswas KK, Oono Y
  • Journal Title: Biological Science in Space Volume: 25 Pages: 45-55
  • URL: http://dx.doi.org/10.2187/bss.25.45
  • Peer Reviewed
• [Presentation] SMALL ACIDIC PROTEIN 1 acts with RUB modification components, the COP9 signalosome and AXR1, to regulate growth and development of Arabidopsis thaliana (2012)
  • Author(s): Oono Y, Nakasone A, Fujiwara, M, Fukao Y, Biswas KK, Rahman A, Kawai-Yamada M, Uchimiya H, Narumi I
  • Organizer: 10th International Congress on Plant Molecular Biology
  • Place of Presentation: ICC Jeju (韓国 チェジュ)
  • Year and Date: 20121021-26
• [Presentation] ユビキチン様タンパク質(RUB) 修飾におけるSMALL ACIDIC PROTEIN 1 (SMAP1) の役割 (2012)
  • Author(s): 大野 豊、鳴海 一成
  • Organizer: 第53回植物生理学会年会
  • Place of Presentation: 京都産業大学 (京都府)
  • Year and Date: 2012-03-16
• [Presentation] 2,4-D 応答に関わる遺伝子Small Acidic Protein 1 (SMAP1)のCOP9 シグナロゾームとのシロイヌナズナにおける遺伝学的相互作用 (2011)
  • Author(s): 大野豊,中曽根光,鳴海一成
  • Organizer: 第52回日本植物生理学会
  • Place of Presentation: 東北大学(仙台)
  • Year and Date: 20110320-22
• [Presentation] Genetic Interaction between AXR1 and SMAP1 that Mediate 2,4-D response in Arabidopsis. (2010)
  • Author(s): Oono Y, Nakasone A, Uchimiya H, Narumi I
  • Organizer: 21st International Conference on Arabidopsis Research
  • Place of Presentation: パシフィコ横浜 (横浜)
  • Year and Date: 20100606-10
• [Remarks]
  • URL: http://www.taka.jaea.go.jp/rab_div/grr/index_j.html
• [Patent(Industrial Property Rights)] 植物のオーキシンおよびオーキシン系除草剤の感受性に関わる新規遺伝子 (2012)
  • Inventor(s): 大野 豊、ラーマン アビドゥール
  • Industrial Property Rights Holder: 独立行政法人日本原子力研究開発機構
  • Industrial Property Number: 特許,第4942082 号
  • Acquisition Date: 2012-03-09