2012 Fiscal Year Final Research Report
Do HOX genes in the visceral mesoderm control regional differentiationof the endoderm?
| Project/Area Number |
22570205
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Developmental biology
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| Research Institution | Yamaguchi University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
HARADA Yumiko 山口大学, 大学院・理工学研究科, 助教 (70284239)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 器官形成 |
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| Research Abstract |
This research project was undertaken in order to elucidate roles of HOX genes in the visceral mesoderm of Drosophila midgut. During the research period
epithelial genes suitable as specific markers for regional differentiation of the midgut were identified
and phenotypes of the mutants and misexpression of HOX genes were analyzed.
It was demonstrated that roles of HOX genes in the visceral mesoderm are induction and regulation of regional differentiation of the underlying endoderm.
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Research Products
(7 results)
