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2012 Fiscal Year Final Research Report

New understanding of fish regulatory T lymphocytes by LAG-3 molecule analysis

Research Project

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Project/Area Number 22580213
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field General fisheries
Research InstitutionFujita Health University

Principal Investigator

DIJKSTRA Johannes M.  藤田保健衛生大学, 総合医科学研究所, 助教 (10387681)

Co-Investigator(Renkei-kenkyūsha) NAKANISHI Teruyuki  日本大学, 生物資源科学部獣医学科, 名誉教授 (00322496)
Project Period (FY) 2010 – 2012
Keywords魚病
Research Abstract

Considerable progress in understanding presumable markers of the fish regulatory T cell system was achieved, including LAG-3, MHC class II, interleukin 15 receptor alpha(IL-15Rα) and interleukin 2 (IL-2).

  • Research Products

    (6 results)

All 2013 2012 2011 2010

All Journal Article (4 results) Presentation (2 results)

  • [Journal Article] Clonal growth of carp (Cyprinus carpio) T cells in vitro: long-term proliferation of Th2-like cells2013

    • Author(s)
      Yamaguchi T, Katakura F, Someya K,Dijkstra JM, Moritomo T, Nakanishi T
    • Journal Title

      Fish & Shellfish Immunology

      Volume: 34(2) Pages: 433-442

    • DOI

      doi:10.1016/j.fsi.2012.11.005

  • [Journal Article] G6f-like is an ITAM-containing collagen receptor in thrombocytes.2012

    • Author(s)
      Hughes CE, Radhakrishnan UP, Lordkipanidze M, Egginton S, Dijkstra JM, Jagadeeswaran P, Watson SP
    • Journal Title

      PLoS One

      Volume: 7(12) Pages: e52622

    • DOI

      doi:10.1371/journal.pone.0052622

  • [Journal Article] The expression of CD8α discriminates distinct T cell subsets in teleost fish.2012

    • Author(s)
      Takizawa F, Dijkstra JM, Kotterba P, Koryta? T, Kock H, Kollner B, Jaureguiberry B, Nakanishi T, Fischer U
    • Journal Title

      Developmental & Comparative Immunology

      Volume: 35(7) Pages: 752-763

    • DOI

      doi:10.1016/j.dci.2011.02.008

  • [Journal Article] Constitutive high expression of interleukin-4/13A and GATA-3 in gill and skin of salmonid fishes suggests that these tissues formTh2-skewed immune environments.2011

    • Author(s)
      Takizawa F, Koppang EO, Ohtani M, Nakanishi T, Hashimoto K, FischerU,Dijkstra JM
    • Journal Title

      Molecular Immunology

      Volume: 48(12-13) Pages: 1360-1368

    • DOI

      doi:10.1016/j.molimm.2011.02.014

  • [Presentation] MHC in salmonid fish and its linkage associations with disease resistance and social behaviour2010

    • Author(s)
      J.M. Dijkstra, M. Ototake, N.Nakanishi, K
    • Organizer
      Hashimoto. 9th International Veterinary Immunology Symposium
    • Place of Presentation
      Tokyo,Japan
    • Year and Date
      20100800
  • [Presentation] Thrombocytes and erythrocytes in teleost fish express a surface marker related to mammalian G6F with a cytoplasmic tail bearing an ITAM.2010

    • Author(s)
      J.M. Dijkstra, K. Ohashi, F. Takizawa, H. Toda, T. Nakanishi and K. Hashimoto
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      20100800

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Published: 2014-08-29  

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