2012 Fiscal Year Final Research Report
Improvement of in vitro production system for porcine embryos by elucidation of mechanism for oocyte maturation in a chemically defined medium
| Project/Area Number |
22580324
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Applied animal science
|
|---|
| Research Institution | National Agriculture and Food Research Organization |
|---|
Principal Investigator |
YOSHIOKA Koji 独立行政法人農業・食品産業技術総合研究機構, 動物衛生研究所・病態研究領域, 上席研究員 (20355192)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
HOSHI Hiroyoshi 株式会社機能性ペプチド研究所, 取締役所長 (50500708)
MITO Tomomi 株式会社機能性ペプチド研究所, 研究員
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Keywords | 発生・分化 / 卵子成熟 |
|---|
| Research Abstract |
The addition of follicle-stimulating hormone (FSH) and tansforming growth factor (TGF)-α to the defined IVM medium synergistically enhanced nuclear maturation, cumulus expansion and the developmental ability of porcine embryos. FSH and TGF-α appear to enhance porcine oocyte maturation through cumulus cells by partly different modes of action. Exogenous hyaluronan and proteoglycan binding link protein 1 and versican also stimulated cumulus expansion.
|
Research Products
(5 results)
