2011 Fiscal Year Final Research Report
Divergent syntheses of biologically active compounds based on catalytic cascade cyclization reactions
| Project/Area Number |
22590005
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Kyoto University |
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Principal Investigator |
OHNO Hiroaki 京都大学, 大学院・薬学研究科, 准教授 (30322192)
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| Project Period (FY) |
2010 – 2011
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| Keywords | 有機化学 |
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| Research Abstract |
As a fundamental research for drug discovery based on environmentallybenign syntheses(e. g. catalytic, cascade, and atom-economical reactions), short-step syntheses of biologically active natural compounds were investigated. This study has reached the original goal by completion of successful total syntheses of biologically active ergot/isoquinoline alkaloids and sphingolipids using divergent and short-step approach.
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