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2012 Fiscal Year Final Research Report

Chemical syntheses of oligosaccharides to elucidate in diagnosis of parasite infection

Research Project

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Project/Area Number 22590014
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Chemical pharmacy
Research InstitutionKeio University

Principal Investigator

HADA Noriyasu  慶應義塾大学, 薬学部, 准教授 (70296531)

Project Period (FY) 2010 – 2012
Keywords糖鎖合成 / 宿主・寄生相互作用 / 糖脂質 / 糖タンパク質 / 寄生虫
Research Abstract

The oligosaccharide residues of glycoprotein and glycosphingolipids in mammalian tissues have been extensively studied for various biological recognition in recent years. In contrast, much less time has been devoted to structures of oligosaccharides from

  • Research Products

    (6 results)

All 2013 2012 2011 2010

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (2 results)

  • [Journal Article] Synthetic studies on glycosphingolipids from protostomia phyla:synthesis of glycosphingolipids and related carbohydrate moieties from the parasite Schistosoma mansoni2012

    • Author(s)
      T. Kanaya, F. Schweizer, T. Takeda, F. Kiuchi, N. Hada.
    • Journal Title

      Carbohydr. Res.

      Volume: 361 Pages: 55-72

    • Peer Reviewed
  • [Journal Article] Synthesis, antigenicity against human sera and structure-activities relationships of carbohydrate moieties from toxocara larvae and their analogues2012

    • Author(s)
      A. Koizumi, K. Yamano , T. Tsuchiya, F. Schweizer , F. Kiuchi, N. Hada.
    • Journal Title

      molecules

      Volume: 17 Pages: 9023-9042

    • Peer Reviewed
  • [Journal Article] Galα1-4Galβ1-3GalNAc is the dominant epitope of Em2 antigen, the mucin-type glycoprotein from Echinococcus multilocularis2012

    • Author(s)
      K. Yamano, A. Koizumi, T. Takeda, F. Kiuchi, N. Hada.
    • Journal Title

      Parasitol. Res

      Volume: 111 Pages: 795-805

    • Peer Reviewed
  • [Journal Article] Synthesis of the carbohydrate moiety from the parasite Echinococcus multilocularis and their antigenicity against human sera2011

    • Author(s)
      A. Koizumi, K. Yamano , F. Schweizer , T. Takeda, F. Kiuchi, N. Hada.
    • Journal Title

      Eur. J. Med. Chem.

      Volume: 46 Pages: 1768-1778

    • Peer Reviewed
  • [Presentation] 無脊椎動物由来糖脂質の合成研究(51) ブタ回虫 Ascaris suum 由来非還元末端糖鎖の合成(7)2013

    • Author(s)
      塚本達也、梅田悠奈、羽田紀康、木内文之
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-29
  • [Presentation] Echinococcus granulosus 由来糖タンパク質の糖鎖部分に関する合成研究2010

    • Author(s)
      大鐘真実、羽田紀康、土屋貴志、中根洋美、小泉明彦、木内文之、山野公明
    • Organizer
      日本薬学会第132 年会
    • Place of Presentation
      札幌
    • Year and Date
      2010-03-30

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Published: 2014-08-29  

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