2012 Fiscal Year Final Research Report
Oxidative stress imaging in organelle by novel TEMPO derivatives
| Project/Area Number |
22590103
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Drug development chemistry
|
|---|
| Research Institution | Nagoya City University |
|---|
Principal Investigator |
NAKAGAWA Hidehiko 名古屋市立大学, 大学院・薬学研究科, 准教授 (80281674)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
MIYATA Naoki 名古屋市立大学, 大学院・薬学研究科, 教授 (50114674)
SUZUKI Takayoshi 名古屋市立大学, 大学院・薬学研究科, 講師 (90372838)
TSUMOTO Hiroki 名古屋市立大学, 大学院・薬学研究科, 特任助教 (00409385)
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Keywords | 生物活性物質 / 活性酸素種 |
|---|
| Research Abstract |
Chemical probes for measuring and imaging nuclei-specific oxidative stress have been synthesized. The probes were fluorescent and responsible to cellular oxidative stress, and one of them was applicable to in vivo-ESR imaging.
|
