2012 Fiscal Year Final Research Report
Development of practical and efficient determination methods for residual veterinary drugs in Japanese cuisine
| Project/Area Number |
22590128
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Environmental pharmacy
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| Research Institution | Aichi Prefectural Institute of Public Health |
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Principal Investigator |
ITO Yuko 愛知県衛生研究所, 衛生化学部, 主任研究員 (80470178)
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| Co-Investigator(Kenkyū-buntansha) |
GOTO Tomomi 愛知県衛生研究所, 衛生化学部, 主任研究員 (10450868)
MIKAMI Eiichi 愛知県衛生研究所, 衛生化学部, 主任研究員 (80450865)
IKAI Yoshitomo 愛知県衛生研究所, 衛生化学部, 室長 (70450872)
HAYASI Rumiko 愛知県衛生研究所, 衛生化学部, 部長 (30450860)
TANAHASHI Takashi 愛知県衛生研究所, 衛生化学部, 主任研究員 (70525766)
OSHIMA Harumi 愛知県衛生研究所, 衛生化学部, 室長 (60450863)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 食品衛生 / 加工食品 / 動物用医薬品 / 残留分析 |
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| Research Abstract |
In many cases, it is difficult to determine the residual veterinary drugs in processed food owing to their degenerated fat and proteins, and some seasonings. Simple and practical determination methods of triphenylmethane-dyes and their major metabolites, benzimidazole anthelmintics and their major metabolites, sulfonamides and quinolone antibacterial residues in Japanese cuisine by LC/MS/MS have been successfully developed. The sample preparation system involves the use of organic solvent for extraction and dual-counter-current chromatography or solid phase extraction for clean-up.
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