2012 Fiscal Year Final Research Report
Exploratory studyof dose adjustmentof oncologic drugs for special populations
| Project/Area Number |
22590142
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Medical pharmacy
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| Research Institution | Keio University |
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Principal Investigator |
IMAMURA Chiyo 慶應義塾大学, 医学部, 講師 (00570954)
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| Co-Investigator(Kenkyū-buntansha) |
TANIGAWARA Yusuke 慶應義塾大学, 医学部, 教授 (30179832)
HIRASAWA Akira 慶應義塾大学, 医学部, 助教 (90296658)
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| Project Period (FY) |
2010 – 2012
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| Keywords | オーダーメイド医療 / PK/PD 解析 / 抗がん剤 / スペシャル・ポピュレーション / 高齢者 / ドセタキセル / 非小細胞肺がん |
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| Research Abstract |
We studied to explore dose adjustment index of docetaxel for elderly patients with advanced or metastatic Non-Small-Cell Lung Cancer. Although there was a trend that docetaxel CL decreased with increasing patient age, there was great interpatient variabil
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