2012 Fiscal Year Final Research Report
Reversal of multidrug resistance by dual inhibitor of anticancer drug efflux transporter and transcription factor.
Project/Area Number |
22590151
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Medical pharmacy
|
Research Institution | Aichi Gakuin University (2012) Nigata University of Phermacy and Applied Life Sciences (2010-2011) |
Principal Investigator |
|
Co-Investigator(Renkei-kenkyūsha) |
NAKAMURA Yutaka 新潟薬科大学, 応用生命科学部, 教授 (20267652)
|
Project Period (FY) |
2010 – 2012
|
Keywords | 医療薬剤学 / 抗がん剤耐性 / 薬剤反応性 / 食品 / 癌 / トランスポータ |
Research Abstract |
Cancer drug resistance is mediated by anticancer drug effluxtransporter and cell survival transcription factor. In this study, I found dualinhibitors of drug efflux transporter and transcription factor from natural compounds. These natural compounds are useful for the development of a new anticancer drug for bettercancer chemotherapy.
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Research Products
(16 results)