2012 Fiscal Year Final Research Report
Study on the dynamic morphofunctional relationships between the neuronal regulation of reproduction, energy control, and stress response in the onset of puberty
| Project/Area Number |
22590230
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Environmental physiology (including Physical medicine and Nutritional physiology)
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| Research Institution | Nippon Medical School |
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Principal Investigator |
OZAWA Hitoshi 日本医科大学, 大学院・医学研究科, 教授 (60169290)
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| Co-Investigator(Kenkyū-buntansha) |
IIJIMA Norio 日本医科大学, 医学部, 准教授 (00285248)
SAWAI Nobuhiko 日本医科大学, 医学部, 助教 (70307916)
YO Shunei 日本医科大学, 医学部, 助教 (70303435)
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| Project Period (FY) |
2010 – 2012
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| Keywords | キスペプチン(kisspeptin) / HPG 軸 / GnRH / 視床下部 / ストレス / エネルギー代謝 / レプチン / グルココルチコイド受容体 |
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| Research Abstract |
We have hisitochemically and molecular biologically studied on the morphofunctional role of kisspeptin and kisspeptin neurons in the hypothalamus which integrate the information about the reproduction, energy balance and stress response in the brain and rely to the HPG axis, and revealed an important role of kisspeptin neurons in the onset of puberty.
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[Journal Article] Direct and specific effect of sevoflurane anesthesia on rat Per2 expression in the supurachiasmatic nucleus2013
Author(s)
Anzai M, Iijima N, Higo S, Takumi K, Matsuo I, Mori K, Ohe Y, Kadota K, Akimoto T, Sakamoto A, Ozawa H
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Journal Title
PLOS 0NE
Volume: 8
Pages: 1-9
Peer Reviewed
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[Journal Article] Identification, Localisation andFunctional lmplication of 26RFa Orthologue Peptide in the Brain of Zebra Finch (Taeniopygia guttata)2011
Author(s)
Tobari Y., Iijima N., Tsunekawa K., Osugi T., Haraguchi S., Ubuka T., Ukena K., Okanoya K., Tsutsui K., Ozawa H
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Journal Title
J.Neuroendocrinology
Volume: 23
Pages: 791-803
Peer Reviewed
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