2012 Fiscal Year Final Research Report
Regulation of stress activated protein kinase pathway by protein phosphatase 2C
| Project/Area Number |
22590280
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Pathological medical chemistry
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| Research Institution | Tohoku University |
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Principal Investigator |
TAMURA Shinri 東北大学, 加齢医学研究所, 教授 (20124604)
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| Co-Investigator(Kenkyū-buntansha) |
KOBAYASHI Takayasu 東北大学, 加齢医学研究所, 准教授 (10221970)
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| Project Period (FY) |
2010 – 2012
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| Keywords | プロテインホスファターゼ |
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| Research Abstract |
In this study we identified acyl CoA binding domain containing 3 (ACBD3) as a binding partner of PPM1L and suggested that ACBD3 recruits PPM1L to the ER-Golgi membrane contact site. We also demonstrated that PPM1L interacts with GOLD(Golgi dynamics) domain that exists in several proteins involved in Golgi function.
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[Journal Article] Acyl-CoA binding domain containing 3 (ACBD3) recruits the protein phosphatase PPM1L to ER-Golgi membrane contact sites2012
Author(s)
Shinoda, Y., Fujita, K., Saito, S., Matsui, H., Kanto, Y., Nagaura, Y., Fukunaga, K., Tamura, S. and Kobayashi, T.
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Journal Title
FEBS Lett
Volume: 586
Pages: 3024-3029
DOI
Peer Reviewed
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