2012 Fiscal Year Final Research Report
Study for metabolic regulatory mechanism by a mitochondrial protein and a sex hormone
| Project/Area Number |
22590290
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Pathological medical chemistry
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| Research Institution | Jichi Medical University |
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Principal Investigator |
ENDO Hitoshi 自治医科大学, 医学部, 教授 (50221817)
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| Project Period (FY) |
2010 – 2012
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| Keywords | ミトコンドリア / プロヒビチン / 性ホルモン / 核-ミトコンドリア連関 / 脂肪分化 |
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| Research Abstract |
Prohibitin 2 (PHB2) has been reported as a multifunctional protein that mainly localizes in mitochondria and translocates into nucleus in the presence of estrogen receptor and estrogen. Decrease of estrogen level is a major cause of obesity in early post-
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[Journal Article] Translational repression of the McKusick-Kaufman syndrome transcript by unique upstream open reading frames encoding mitochondrial proteins with alternative polyadenylation sites2013
Author(s)
Akimoto, C. Sakashita, E., Kasashima, K., Kuroiwa, K., Tominaga, K., Hamamoto, T., and Endo, H.
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Journal Title
Biochem Biophys Acta
Volume: 1830
Pages: 2728-2738
DOI
Peer Reviewed
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[Journal Article] Epitope determination of anti Thy-1 monoclonal antibodies that regulate neurite outgrowth2012
Author(s)
Kuroiwa, K., Torkai,Y., Osawa, M., Nakashima, T., Nakashima, M., Endo, H., and Arai, T
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Journal Title
Hybridoma
Volume: 31
Pages: 225-232
DOI
Peer Reviewed
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