2012 Fiscal Year Final Research Report
Functional analysis for psoriasis susceptibility gene
| Project/Area Number |
22590304
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Human genetics
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| Research Institution | Tokai University |
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Principal Investigator |
OKA Akira 東海大学, 総合医学研究所, 講師 (80384866)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 尋常性乾癬 / 感受性遺伝子 |
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| Research Abstract |
The aim of this study was to unravel the function of psoriasis-susceptibility gene we found in the previous our study. In this study, we could discover that the genetic risk factor of the gene in Japanese psoriasis was shared with Korean psoriasis. Moreover, the protein produced by the gene could interacted with another protein which was involved in wound healing and skin inflammation characterized as psoriasis-pathogenesis.
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