2012 Fiscal Year Final Research Report
Fundamental study of patholofgival role of CCL8 in GVHD
| Project/Area Number |
22590365
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Experimental pathology
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| Research Institution | Sapporo Medical University |
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Principal Investigator |
KOKAI Yasuo 札幌医科大学, 医学部, 教授 (20178239)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 再生医学 / 造血幹細胞移植 / 移植片対宿主病 / GVHD / バイオマーカー / 客観診断 / 治療効果判定 / 予後予測 |
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| Research Abstract |
The early and preclinical expression of CCL8 in plasma predicts overall survival of GVHD in vivo. Together with an involvement of allorecognition in CCL8 expression, it suggests that CCL8 plays an important role in GVHD pathology.
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Research Products
(5 results)
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[Journal Article] Metalothionein deficiency in the injured peripheral nerves of complex regional pain syndrome as revealed by proteomics2012
Author(s)
Oki G, Wada T, Iba K, Aiki H, Sasaki K, Imai S, Sohm H, Matsumoto K, Yamaguchi M, Fujimiya M, Yamashita T, Kokai Y
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Journal Title
Pain
Volume: 153
Pages: 532-9
Peer Reviewed
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[Journal Article] Early expression of plasma CCL8 closely correlates with survival rate of acute graft-versus-host disease in mice2011
Author(s)
Yamamoto M, Ota A, Hori T, Imai S, Sohma H, Suzuki N, Hatakeyama N, Inazawab N, Ito M-Y, Kimura H, Tsutsumi H, Kokai Y
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Journal Title
Exp Hematol
Volume: 39(11)
Pages: 1101-11112
Peer Reviewed
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