2012 Fiscal Year Final Research Report
ESTABLISH THE INDIVIDUALIZED TREATMENT ON LUNG ADENOCARCINOMA USINGTHE EGFR GENE MUTATION ANALYSIS.
| Project/Area Number |
22590531
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Laboratory medicine
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| Research Institution | Nagasaki University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NAKATOMI Katsumi 長崎大学, 長崎大学病院, 助教 (90457531)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 遺伝子検査学 |
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| Research Abstract |
Intra-tumor heterogeneity of EGFR mutations in patients with mixed-type lung adenocarcinoma was analyzed according to the distribution of histological subtypes. Intra-tumor heterogeneity of EGFR mutations was detected in 9 of 38 tumors, and there was a significant correlation between heterogeneity of EGFR mutations and smoking history (P<0.043).
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Research Products
(12 results)
