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2012 Fiscal Year Final Research Report

Effects of environmental exposure of dioxins on infant development of social emotional behavior

Research Project

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Project/Area Number 22590556
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Hygiene
Research InstitutionKanazawa Medical University

Principal Investigator

NISHIJO Muneko  金沢医科大学, 医学部, 准教授 (40198461)

Co-Investigator(Kenkyū-buntansha) NAKAGAWA Hideaki  金沢医科大学, 医学部, 教授 (00097437)
Co-Investigator(Renkei-kenkyūsha) MORIKAWA Yuko  金沢医科大学, 看護学部, 教授 (20210156)
NAKAMURA Kousi  金沢医科大学, 医学部, 准教授 (80422898)
SAKURAI Masaru  金沢医科大学, 医学部, 准教授 (90397216)
HONDA Tatsuhisa  愛媛大学, 農学部, 教授 (10314973)
Project Period (FY) 2010 – 2012
Keywordsダイオキシン / 小児 / 脳神経発達 / 疫学 / ベトナム / 母乳 / 社会情動発達
Research Abstract

In a dioxin hot spot in Danang, Vietnam, we followed up 230 newborns for 4 months, 1 year and 3 years after birth. Infants whose maternal breast milk contained higher dioxins showed lower neurodevelopmental scores including not only cognitive and motor but also social emotional scales tested by Bayley scales, suggesting that dioxin exposure may influence on social interactions. Although maternal daily dioxin intake was low, food pattern of fish and egg were related to levels of dioxins in breast milk.

  • Research Products

    (17 results)

All 2013 2012 2011

All Journal Article (5 results) (of which Peer Reviewed: 2 results) Presentation (12 results)

  • [Journal Article] Dioxin exposure and infant neurodevelopment; a follow up study in Vietnamese infants2012

    • Author(s)
      Pham The Tai,Muneko Nishijo,Hideaki Nakagawa,etal
    • Journal Title

      Organohalogen Compounds

      Volume: 74巻 Pages: 1369-1372

  • [Journal Article] Effects of dioxins exposure on social emotional behavior of children living in a hot spot area2012

    • Author(s)
      Muneko Nishijo,Pham TheTai,Hideaki Nakagawa,etal.
    • Journal Title

      Vietnam,Organohalogen Compounds

      Volume: 74巻 Pages: 1332-1335

  • [Journal Article] Impact of perinatal dioxin exposure on infant growth: A cross-sectional and longitudinal studies in dioxin contaminated areas in Vietnam2012

    • Author(s)
      Muneko Nishijo,Pham TheTai,Hideaki Nakagawa,etal.
    • Journal Title

      PLoSONE

      Volume: 7巻 Pages: e40273

    • DOI

      DOI:10.1371/journal.pone.0040273

    • Peer Reviewed
  • [Journal Article] Dioxin concentrations in breast milk of Vietnamese nursing mothers; ? A survey after four decades from the end of spraying herbicides?2011

    • Author(s)
      Pham TheTai,Muneko Nishijo,Hideaki Nakagawa,etal.
    • Journal Title

      EnvironSciTech

      Volume: 45巻 Pages: 6625-32

    • DOI

      DOI:10.1021/es201666d

    • Peer Reviewed
  • [Journal Article] Effects of dioxins exposure on infant growth in a hot spot area Vietnam2011

    • Author(s)
      Muneko Nishijo,Pham TheTai,Hideaki Nakagawa,etal.
    • Journal Title

      Organohalogen Compounds

      Volume: 73巻 Pages: 1745-48

  • [Presentation] Relationships between food and dioxin concentrations in breast milk of mothers living in a hot spot of dioxin contamination in Vietnam.2013

    • Author(s)
      Nguyen Thi Nguet Anh,Muneko Nishijo,Hideaki Nakagawa,etal.
    • Organizer
      第83回日本衛生学会総会
    • Place of Presentation
      金沢大学保健学科(金沢市)
    • Year and Date
      2013-03-26
  • [Presentation] Effects of perinatal exposure to dioxins on neurodevelopment in Vietnamese children at 3 years of age.2013

    • Author(s)
      Tran Ngoc Nghi,Muneko Nishijo,Hideaki Nakagawa,etal.
    • Organizer
      第83回日本衛生学会総会
    • Place of Presentation
      金沢大学保健学科(金沢市)
    • Year and Date
      2013-03-26
  • [Presentation] Dioxin health effects on infant growth and neurodevelopment in Vietnam.2012

    • Author(s)
      Muneko Nishijo,Pham TheTai,Hideaki Nakagawa,etal.
    • Organizer
      The 9th Vietnam Scientific Conference on Physiology.
    • Place of Presentation
      フエ(ベトナム)
    • Year and Date
      2012-12-01
  • [Presentation] Effects of dioxin exposure in breast milk of nursing mothers on neurodevelopment of infants in Vietnam.2012

    • Author(s)
      Pham The Tai,Muneko Nishijo,Hideaki Nakagawa,etal.
    • Organizer
      Vietnam
    • Place of Presentation
      フエ(ベトナム)
    • Year and Date
      2012-12-01
  • [Presentation] Dioxin exposure and infant neurodevelopment; a follow up study in Vietnamese infants, 32th International Symposium on Halogenated persistent.2012

    • Author(s)
      Pham TheTai,Muneko Nishijo,Hideaki Nakagawa,etal.
    • Organizer
      OrganicPollutants
    • Place of Presentation
      ケアンズ(オーストラリア)
    • Year and Date
      2012-08-26
  • [Presentation] Effects of dioxins exposure on social emotional behavior of children living in a hot spot area,Vietnam2012

    • Author(s)
      Muneko Nishijo,Pham TheTai,Hideaki Nakagawa,etal.
    • Organizer
      OrganicPollutants
    • Place of Presentation
      ケアンズ(オーストラリア)
    • Year and Date
      2012-08-26
  • [Presentation] Dioxin concentrations in breast milk of Vietnamese nursing mothers: A survey four decades after the herbicide spraying2012

    • Author(s)
      Pham The Tai,Muneko Nishijo,Hideaki Nakagawa,etal.
    • Organizer
      第22回日本疫学会学術総会
    • Place of Presentation
      学術総合センター(東京)
    • Year and Date
      2012-01-27
  • [Presentation] The effects of dioxin on infant growth in dioxin contaminated areas in Danang City-Dioxin Hot Spot in Vietnam2012

    • Author(s)
      Nguyen Thi Nguet Anh,Muneko Nishijo,Hideaki Nakagawa,etal.
    • Organizer
      第22回日本疫学会学術総会
    • Place of Presentation
      学術総合センター(東京)
    • Year and Date
      2012-01-27
  • [Presentation] Effects of dioxins exposure on infant growth in a hot spot area, Vietnam2011

    • Author(s)
      MunekoNishijo Pham The Tai,Hideaki Nakagawa,etal.
    • Organizer
      31th International Symposium on Halogenated persistent Organic Pollutants
    • Place of Presentation
      ブリュッセル(ベルギー)
    • Year and Date
      2011-08-25
  • [Presentation] Effects of Perinatal Exposure to Dioxins (PCDDs/PCDFs) on Neurodevelopment in Vietnamese infants at 4 Months of Age2011

    • Author(s)
      Pham The Tai,Muneko Nishijo,Hideaki Nakagawa,etal.
    • Organizer
      第84回日本産業衛生学会
    • Place of Presentation
      シーサイドホテル(東京)
    • Year and Date
      2011-05-19
  • [Presentation] Individual Daily Intake (IDI) of Dioxin in Mother and Infant Pairs in Danang City-Dioxin Hot Spot in Vietnam.2011

    • Author(s)
      Nguyen Thi Nguet Anh,Muneko Nishijo,Hideaki Nakagawa,etal.
    • Organizer
      第84回日本産業衛生学会
    • Place of Presentation
      シーサイドホテル(東京)
    • Year and Date
      2011-05-19
  • [Presentation] Effects of dioxins (PCDDs/PCDFs) on infant neurodevelopment whose mothers live in an area around a storage of orange agents during Vietnam war2011

    • Author(s)
      Pham The Tai,Muneko Nishijo,Hideaki Nakagawa,etal.
    • Organizer
      第21回日本疫学会
    • Place of Presentation
      北海道立道民活動センター(札幌)
    • Year and Date
      2011-01-22

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Published: 2014-08-29  

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