2012 Fiscal Year Final Research Report
Determination of the biological marker against occupational exposure to antineoplastic drugs in health care workers
| Project/Area Number |
22590572
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Hygiene
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| Research Institution | Osaka Prefectural Institute of Public Health |
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Principal Investigator |
YOSHIDA Jin 大阪府立公衆衛生研究所, 衛生化学部, 研究員 (00332453)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 抗がん剤 / 職業的曝露 / 生物学的指標 / 安全対策 |
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| Research Abstract |
We aimed to develop the quantitation method of the biologica markers of cyclophosphamide and fluorouracil, and evaluate the occupational exposur, level of these drugs among health care workers. As results, alfa-fluoro-beta-alanine (AFBA, a major metabolite of fluorouracil) could be th, useful biological marker to evaluate the occupational exposure level to fluorouracil and dm effectiveness of the control measures
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