2012 Fiscal Year Final Research Report
Significance of impaired glucose tolerance as the risk factor ofmalignant neoplasms and cardiovascular disease: A cohort study
| Project/Area Number |
22590592
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Sapporo Medical University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
OHNISHI Hirohumi 札幌医科大学, 医学部, 准教授 (20359996)
SHIMAMOTO Kazuaki 札幌医科大学, 学長 (40136940)
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| Project Period (FY) |
2010 – 2012
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| Keywords | 耐糖能異常 |
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| Research Abstract |
By means of a cohort study, we evaluated the association between impaired glucose tolerance（IGT）and the occurrence of malignant neoplasms (NEO) and cardiovascular diseases(CVD). In 1986 ・ 1987, inhabitants of 1,989 people were randomly selected and followed for 23.5 years, and the onset and death of both NEOand CVD were registered over this period. As a result, we observed the risk of the NEO and CVD become 2.16 and 2.05, respectively , in comparison with non-IGT in IGT. IGTwas a common risk factor of both NEO and CVD, and the possibility that the management of IGT contributed to the prevention of NEO and CVD in the same way.
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[Journal Article] A single nucleotide polymorphism of the adenosine deaminase, RNA-specific gene is associated with the serum triglyceride level, abdominal circumference, and serum adiponectin concentration2012
Author(s)
Oguro R, Kamide K, Katsuya T, Akasaka H, Congrains A, Arai Y, Hirose N, Saitoh S, Ohishi M, Miura T, Rakugi H
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Journal Title
Exp Gerontol
Volume: 47
Pages: 183-187
Peer Reviewed
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